Faculty

Institution

Unit

Venue

Brian Edwards

Professor

Wayne State University

Affiliations

School of Medicine

Biochemistry, Microbiology and Immunology

Graduate School

Brian Edwards is currently serving as a Biochemistry, Microbiology And Immunology Professor at Wayne State University.

Honors

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Experiences

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Education

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Brian Edwards

Wayne State University

Professor

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molecular biology structural biology biochemistry protein science protein structure enzymes structural molecular biology crystallography biophysics membrane biology pharmacology biological chemistry crystal structures redox biology x-ray crystallography medicinal chemistry protein x-ray crystallography protein chemistry biological inorganic chemistry enzyme catalysis apoptosis protein phosphorylation molecular biophysics cell death enzyme inhibition thrombosis protein engineering biomolecular structure peptides structural chemistry mammalian biology molecular physiology biocatalysis molecular microbiology bacteriology mitochondrial function peptide science protein function x-ray diffraction protein transport aspartate transcarbamylase aquifex aeolicus semisynthetic ribonuclease aspartate transcarbamoylase coordination chemistry biochemical sciences laboratory medicine structural composition biomolecular analysis molecular catalysis trace elements skeletal muscle microbial genetics cell regulation hemostasis protein biosynthesis mitochondrial membrane potential three-dimensional structure arsc arsenate reductase electron density latent dihydroorotase mitochondrial respiration x-ray crystal structure cytokines structure-function enzyme kinetics protein modeling structure elucidation cellular biology gene characterization cellular enzymology functional modification tissue-specific regulation post-translational modifications bovine thrombin complexes human fibrinogen bound human gene variant pyrimidine biosynthesis arsenic resistance biosynthesis

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Amyloid Accelerator Polyphosphate Fits as the Mystery Density in α-Synuclein Fibrils. PLoS Biology (2024)

Philipp HuettemannPavithra MahadevanJustine LempartEric TseBudheswar DehuryBrian F. P. EdwardsDaniel R. SouthworthBikash R. SahooUrsula Jakob

neurodegenerative diseasesprotein scienceneuroscienceprotein structurea-synuclein fibrilsmolecular biophysicsstructural compositionmolecular biologymembrane biologytrace elementsmolecular neurodegenerationprotein phosphorylationimmunologyvascular biologymystery densityinflammationprotein transportbiopolymersamyotrophic lateral sclerosisbiophysical review

Phosphorylations and Acetylations of Cytochrome C Control Mitochondrial Respiration, Mitochondrial Membrane Potential, Energy, Ros, and Apoptosis. Cells (2024)

Paul T. MorseTasnim ArroumJunmei WanLucynda PhamAsmita VaishnavJamie BellLauren PavelichMoh H. MalekThomas H. SandersonBrian F.P. EdwardsMaik Hüttemann

apoptosismitochondrial membrane potentialcell biologymitochondrial respirationbiochemistrymembrane biologymolecular biology

Cytochrome C Lysine Acetylation Regulates Cellular Respiration and Cell Death in Ischemic Skeletal Muscle. Nature Communications (2023)

Paul T. MorseGonzalo Pérez-MejíasJunmei WanAlice A. TurnerInmaculada MárquezHasini A. KalpageAsmita VaishnavMatthew P. ZurekPhilipp P. HuettemannKatherine KimTasnim ArroumMiguel A. De la RosaDipanwita Dutta ChowdhuryIcksoo LeeJoseph S. BrunzelleThomas H. SandersonMoh H. MalekDavid MeierhoferBrian F. P. EdwardsIrene Díaz-MorenoMaik Hüttemann

mitochondrial functionliver physiologymolecular and cellular biologyskeletal musclecellular respirationischemic skeletal musclemuscle functionneuroscienceredox biologymembrane biologyphysiologymolecular biologyprotein functionneurophysiologycell deathcellular physiologymolecular physiology

Structural Analysis and Functional Evaluation of the Disordered ß–Hexosyltransferase Region From Hamamotoa (Sporobolomyces) Singularis. Frontiers in Bioengineering and Biotechnology (2023)

Suzanne F. DagherAsmita VaishnavChristopher B. StanleyFlora MeilleurBrian F. P. EdwardsJosé M. Bruno-Bárcena

disordered ss-hexosyltransferase regionbiomolecular engineeringfunctional evaluationbiological engineeringbiomedical engineeringbiotechnologystructural biology

The Ancient and Evolved Mouse Sperm-Associated Antigen 6 Genes Have Different Biologic Functions in Vivo. Cells (2022)

Yi Tian YapWei LiQi ZhouSarah Haj-DiabDipanwita Dutta ChowdhuryAsmita VaishnavPamela HardingDavid C. WilliamsBrian F. EdwardsJerome F. StraussZhibing Zhang

reproductive biologygeneticsgene expressionin vivo systemscell biologymammalian biologymolecular biology

Lysine 53 Acetylation of Cytochrome C in Prostate Cancer: Warburg Metabolism and Evasion of Apoptosis. Cells (2021)

Viktoriia BazylianskaHasini A. KalpageJunmei WanAsmita VaishnavGargi MahapatraAlice A. TurnerDipanwita Dutta ChowdhuryKatherine KimPaul T. MorseIcksoo LeeJoseph S. BrunzelleLisa PolinPrabal SubediElisabeth I. HeathIzabela PodgorskiKatrin MarcusBrian F.P. EdwardsMaik Hüttemann

warburg metabolismurologytumor biologymitochondrial functionapoptosisoncologycancer researchredox biologymembrane biologyprostate cancermolecular biologycell deathneurology

Characterization and Assembly of the Pseudomonas Aeruginosa Aspartate Transcarbamoylase-Pseudo Dihydroorotase Complex. PLoS ONE (2020)

Chandni PatelAsmita VaishnavBrian F. P. EdwardsDavid R. Evans

enzymesgene expressionmolecular microbiologymicrobial pathogenesisprotein sciencemolecular regulationbiochemistryimmunologypseudomonas aeruginosatranscarbamoylase-pseudo dihydroorotase complexmolecular biologysequence assemblystructural biologyprotein assembly

Cytochrome C Phosphorylation: Control of Mitochondrial Electron Transport Chain Flux and Apoptosis. The International Journal of Biochemistry & Cell Biology (2020)

Hasini A. KalpageJunmei WanPaul T. MorseMatthew P. ZurekAlice A. TurnerAntoine KhobeirNabil YazdiLara HakimJenney LiuAsmita VaishnavThomas H. SandersonMaurice-Andre RecanatiLawrence I. GrossmanIcksoo LeeBrian F.P. EdwardsMaik Hüttemann

apoptosiscell biologybiochemistrymembrane biologymolecular biologycell death

ORYZOCYTOSIS: A Novel Morphological Variant of Hereditary Elliptocytosis Associated With a Novel Mutation in β-Spectrin (Sptb C154 C Gt;T P.Arg52Trp). Blood (2019)

Alexander GlarosManisha GadgeelShruti BaglaSteven BuckRoland ChuYaddanapudi RavindranathBrian EdwardsAsmita Vaishnav

hematologygeneticsnovel mutationdermatologyhereditary elliptocytosismolecular biology

Pressure-Induced Activation of Latent Dihydroorotase From Aquifex Aeolicus as Revealed by High Pressure Protein Crystallography.. FEBS Journal (2019)

Thierry PrangéEric GirardRoger FourmeAnne‐Claire DhaussyBrian EdwardsAsmita VaishnavChandni PatelHedeel Guy‐EvansGuy HervéDavid R. Evans

pressure-induced activationenzymesbiochemistryfish biologylatent dihydroorotaseaquifex aeolicusstructural biology

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Brian Edwards

Professor

Wayne State University

Affiliations

School of Medicine

Biochemistry, Microbiology and Immunology

Graduate School

Brian Edwards is currently serving as a Biochemistry, Microbiology And Immunology Professor at Wayne State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Brian Edwards

Wayne State University

Professor

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Amyloid Accelerator Polyphosphate Fits as the Mystery Density in α-Synuclein Fibrils. PLoS Biology (2024)

Philipp HuettemannPavithra MahadevanJustine LempartEric TseBudheswar DehuryBrian F. P. EdwardsDaniel R. SouthworthBikash R. SahooUrsula Jakob

Phosphorylations and Acetylations of Cytochrome C Control Mitochondrial Respiration, Mitochondrial Membrane Potential, Energy, Ros, and Apoptosis. Cells (2024)

Paul T. MorseTasnim ArroumJunmei WanLucynda PhamAsmita VaishnavJamie BellLauren PavelichMoh H. MalekThomas H. SandersonBrian F.P. EdwardsMaik Hüttemann

apoptosismitochondrial membrane potentialcell biologymitochondrial respirationbiochemistrymembrane biologymolecular biology

Cytochrome C Lysine Acetylation Regulates Cellular Respiration and Cell Death in Ischemic Skeletal Muscle. Nature Communications (2023)

Structural Analysis and Functional Evaluation of the Disordered ß–Hexosyltransferase Region From Hamamotoa (Sporobolomyces) Singularis. Frontiers in Bioengineering and Biotechnology (2023)

Suzanne F. DagherAsmita VaishnavChristopher B. StanleyFlora MeilleurBrian F. P. EdwardsJosé M. Bruno-Bárcena

disordered ss-hexosyltransferase regionbiomolecular engineeringfunctional evaluationbiological engineeringbiomedical engineeringbiotechnologystructural biology

The Ancient and Evolved Mouse Sperm-Associated Antigen 6 Genes Have Different Biologic Functions in Vivo. Cells (2022)

Yi Tian YapWei LiQi ZhouSarah Haj-DiabDipanwita Dutta ChowdhuryAsmita VaishnavPamela HardingDavid C. WilliamsBrian F. EdwardsJerome F. StraussZhibing Zhang

reproductive biologygeneticsgene expressionin vivo systemscell biologymammalian biologymolecular biology

Lysine 53 Acetylation of Cytochrome C in Prostate Cancer: Warburg Metabolism and Evasion of Apoptosis. Cells (2021)

warburg metabolismurologytumor biologymitochondrial functionapoptosisoncologycancer researchredox biologymembrane biologyprostate cancermolecular biologycell deathneurology

Characterization and Assembly of the Pseudomonas Aeruginosa Aspartate Transcarbamoylase-Pseudo Dihydroorotase Complex. PLoS ONE (2020)

Chandni PatelAsmita VaishnavBrian F. P. EdwardsDavid R. Evans

Cytochrome C Phosphorylation: Control of Mitochondrial Electron Transport Chain Flux and Apoptosis. The International Journal of Biochemistry & Cell Biology (2020)

apoptosiscell biologybiochemistrymembrane biologymolecular biologycell death

ORYZOCYTOSIS: A Novel Morphological Variant of Hereditary Elliptocytosis Associated With a Novel Mutation in β-Spectrin (Sptb C154 C Gt;T P.Arg52Trp). Blood (2019)

Alexander GlarosManisha GadgeelShruti BaglaSteven BuckRoland ChuYaddanapudi RavindranathBrian EdwardsAsmita Vaishnav

hematologygeneticsnovel mutationdermatologyhereditary elliptocytosismolecular biology

Pressure-Induced Activation of Latent Dihydroorotase From Aquifex Aeolicus as Revealed by High Pressure Protein Crystallography.. FEBS Journal (2019)

Thierry PrangéEric GirardRoger FourmeAnne‐Claire DhaussyBrian EdwardsAsmita VaishnavChandni PatelHedeel Guy‐EvansGuy HervéDavid R. Evans

pressure-induced activationenzymesbiochemistryfish biologylatent dihydroorotaseaquifex aeolicusstructural biology

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10 / page

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