Faculty

Institution

Unit

Venue

Breann Brown

Assistant Professor of Biochemistry

Vanderbilt University

Affiliations

School of Medicine

Department of Biochemistry

Breann Brown is currently serving as a Biochemistry Assistant Professor of Biochemistry at Vanderbilt University.

Honors

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Experiences

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Education

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Breann Brown

Vanderbilt University

Assistant Professor of Biochemistry

You can click a keyword to filter the displayed items

molecular biology biochemistry enzymes structural biology protein science structural molecular biology protein structure biological chemistry biophysics immunology membrane biology gene expression heme signaling structural basis immune responses molecular medicine molecular biophysics clinical biochemistry biochemical sciences structural chemistry molecular science biomolecular structure redox biology molecular metabolism bioenergetics cell metabolism cellular immune responses innate immune system host factors adaptive immune system structure-function enzyme kinetics protein misfolding molecular basis protein expression protein assembly single molecule biophysics key site protein chemistry structural bioinformatics structural composition heme homeostasis heme trafficking heme transport mitochondrial function yeast cancer genetics mutagenesis molecular biological method anti-helminth immunity cellular context human disease aminolevulinic acid synthase plp-dependent enzymes enzyme structure heterologous expression eukaryotic ala synthase structure-based insights heme biosynthesis protein x-ray crystallography x-ray crystallography

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Reversible Feedback Mechanism Regulating Mitochondrial Heme Synthesis. Journal of Biological Chemistry (2025)

heme signalingmitochondrial functionenzymesmolecular metabolismbiological chemistrymetabolic pathwaysbioenergeticsbiochemistrycell metabolism

Elucidating the Role of Human Alas2 C-Terminal Mutations Resulting in Loss of Function and Disease. Biochemistry (2024)

Jessica L. TaylorPedro H. Ayres-GalhardoBreann L. Brown

gene expressioncancer geneticsmutagenesisgeneticsmolecular biologyhuman geneticsbiochemistry

Heterologous Expression and Purification of Eukaryotic Ala Synthase From E. Coli. Methods in molecular biology (2024)

Breann L Brown

heterologous expressioneukaryotic ala synthasemolecular biologymolecular biological method

The Yeast Ala Synthase C‐Terminus Positively Controls Enzyme Structure and Function. Protein Science (2023)

Jenny U. TranBreann L. Brown

yeastgeneticsenzymesmolecular biologystructural molecular biologystructural biologyprotein scienceenzyme structurebiochemistry

Structural Basis for Allostery in Plp-Dependent Enzymes. Frontiers in Molecular Biosciences (2022)

Jenny U. TranBreann L. Brown

plp-dependent enzymesprotein structurestructural chemistrybiochemistrysingle molecule biophysicsmolecular sciencekey siteenzymesbiomolecular structurestructural biologyprotein sciencemembrane biologymolecular biophysicsprotein chemistrystructural bioinformaticsstructural basisbiophysicsmolecular biologystructural molecular biologystructural composition

Structural Basis for Dysregulation of Aminolevulinic Acid Synthase in Human Disease. Journal of Biological Chemistry (2022)

Jessica L. TaylorBreann L. Brown

structure-function enzyme kineticsprotein structurebiological chemistryhuman diseasebiochemistryclinical biochemistryenzymesstructural biologybiochemical sciencesprotein sciencemembrane biologyprotein misfoldingstructural basispharmacologymolecular biologystructural molecular biologymolecular basisprotein expressionaminolevulinic acid synthasemolecular medicine

Handling Heme With Care. Nature Chemical Biology (2021)

Breann L. BrownT. M. Iverson

heme signalingheme homeostasisredox biologychemical biologybiomolecular engineeringheme traffickingmolecular biologybiological chemistrychemistryheme transport

Cellular Context of Il-33 Expression Dictates Impact on Anti-Helminth Immunity. Science Immunology (2020)

Li-Yin HungYukinori TanakaKarl HerbineChristopher PastoreBrenal SinghAnnabel FergusonNisha VoraBonnie DouglasKelly ZulloEdward M. BehrensTiffany Li Hui TanMichael A. KohanskiPaul BryceCailu LinTaku KambayashiDanielle R. ReedBreann L. BrownNoam A. CohenDe’Broski R. Herbert

immunologygene expressioncellular immune responsesinnate immune systemhost factorsadaptive immune systemanti-helminth immunityimmune responsescellular contextcell biology

Structure‐Based Insights Into Control of Heme Biosynthesis. The FASEB Journal (2020)

Breann L. BrownJulia R. KardonTania A. Baker

immunologystructure-based insightsheme biosynthesissystems biologygeneticsstructural biologyprotein science

N Domain of the Lon Aaa+ Protease Controls Assembly and Substrate Choice. Protein Science (2018)

Breann L. BrownEllen F. VieuxTejas KalastavadiSaRa KimJames Z. ChenTania A. Baker

biophysicsprotein assemblyenzymesstructural biologyprotein science

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Breann Brown

Assistant Professor of Biochemistry

Vanderbilt University

Affiliations

School of Medicine

Department of Biochemistry

Breann Brown is currently serving as a Biochemistry Assistant Professor of Biochemistry at Vanderbilt University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Breann Brown

Vanderbilt University

Assistant Professor of Biochemistry

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Reversible Feedback Mechanism Regulating Mitochondrial Heme Synthesis. Journal of Biological Chemistry (2025)

heme signalingmitochondrial functionenzymesmolecular metabolismbiological chemistrymetabolic pathwaysbioenergeticsbiochemistrycell metabolism

Elucidating the Role of Human Alas2 C-Terminal Mutations Resulting in Loss of Function and Disease. Biochemistry (2024)

Jessica L. TaylorPedro H. Ayres-GalhardoBreann L. Brown

gene expressioncancer geneticsmutagenesisgeneticsmolecular biologyhuman geneticsbiochemistry

Heterologous Expression and Purification of Eukaryotic Ala Synthase From E. Coli. Methods in molecular biology (2024)

Breann L Brown

heterologous expressioneukaryotic ala synthasemolecular biologymolecular biological method

The Yeast Ala Synthase C‐Terminus Positively Controls Enzyme Structure and Function. Protein Science (2023)

Jenny U. TranBreann L. Brown

yeastgeneticsenzymesmolecular biologystructural molecular biologystructural biologyprotein scienceenzyme structurebiochemistry

Structural Basis for Allostery in Plp-Dependent Enzymes. Frontiers in Molecular Biosciences (2022)

Jenny U. TranBreann L. Brown

Structural Basis for Dysregulation of Aminolevulinic Acid Synthase in Human Disease. Journal of Biological Chemistry (2022)

Jessica L. TaylorBreann L. Brown

Handling Heme With Care. Nature Chemical Biology (2021)

Breann L. BrownT. M. Iverson

heme signalingheme homeostasisredox biologychemical biologybiomolecular engineeringheme traffickingmolecular biologybiological chemistrychemistryheme transport

Cellular Context of Il-33 Expression Dictates Impact on Anti-Helminth Immunity. Science Immunology (2020)

immunologygene expressioncellular immune responsesinnate immune systemhost factorsadaptive immune systemanti-helminth immunityimmune responsescellular contextcell biology

Structure‐Based Insights Into Control of Heme Biosynthesis. The FASEB Journal (2020)

Breann L. BrownJulia R. KardonTania A. Baker

immunologystructure-based insightsheme biosynthesissystems biologygeneticsstructural biologyprotein science

N Domain of the Lon Aaa+ Protease Controls Assembly and Substrate Choice. Protein Science (2018)

Breann L. BrownEllen F. VieuxTejas KalastavadiSaRa KimJames Z. ChenTania A. Baker

biophysicsprotein assemblyenzymesstructural biologyprotein science

1
2
10 / page

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Similar Faculty Members

Patrick Loll

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Drexel University

protein structure

biomolecular structure

Dmitry Vassylyev

Institution

University of Alabama at Birmingham

protein structure

chromatographic technology

Arun Malhotra, Ph.D.

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University of Miami

protein science

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protein structure

Anthony Kossiakoff

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Li Fan

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Katsuhiko Murakami

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