Faculty

Institution

Unit

Venue

Braden Lobingier

Assistant Professor of Chemical Physiology and Biochemistry

Oregon Health & Science University

Affiliations

OHSU School of Medicine

Bob And Charlee Moore Institute For Nutrition And Wellness

Center Of The Amyloidosis

Division Of Cardiology

OGI School of Science and Engineering

Department Of Chemistry, Biochemistry And Molecular Biology

Department Of Physiology And Pharmacology

Oregon Health & Science University

Bob And Charlee Moore Institute For Nutrition And Wellness

School Of Medicine

Division Of Cardiology

School Of Medicine

Braden Lobingier is currently serving as a Bob And Charlee Moore Institute For Nutrition And Wellness Assistant Professor of Chemical Physiology and Biochemistry at Oregon Health & Science University.

Honors

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Experiences

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Education

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Braden Lobingier

Oregon Health & Science University

Assistant Professor of Chemical Physiology and Biochemistry

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molecular biology cell biology receptors protein science pharmacology signal transduction cell signaling receptor (biochemistry) g protein-coupled receptor neuropharmacology chemical biology molecular cell biology pharmacological research intracellular trafficking structural biology endocytic pathway systems biology biological chemistry cellular biochemistry peptides signaling pathways crispr neurons biosensors medicinal research photomedicine addiction medicine pharmacotherapy structural molecular biology molecular physiology molecular regulation photodynamic therapy cell trafficking molecular pathways molecular sorting mechanisms of action proximal proteome engineered trafficking biosensor real-time optical control enzyme inhibition mammalian biology neuropsychopharmacology future medicinal chemistry interactomics transcription regulation receptor tyrosine kinases biochemical interaction biomolecular interactions cannabis use non-peptide ligand chemical probes photoreceptor cells phototoxicity molecular research gene editing neuropeptide receptors drug targets molecular pain secretory pathway opioid use disorder reflection removal light regulation protein interaction networks living cells opioid drug action receptor-mediated signaling subunit organization endolysosomal membrane traffic rab interactions vps-c protein complexes protein-coupled receptor activation subcellular location shapes quaternary snare complex activated m-opioid receptor cellular perspective

Notable Scholarly Works

Notable Federal Grants

Collaborators

Endosomal Sorting of the Glucagon-Like Peptide-1 Receptor (Glp-1R) is Controlled by the Retromer Complex (Abstract Id: 271201). Journal of Pharmacology and Experimental Therapeutics (2026)

g protein-coupled receptorreceptorspeptidespharmacological researchcell biology

Lysosomal Down-Regulation of the Mu Opioid Receptor is Opposed by the Retromer Complex. Science Advances (2026)

receptorslysosomal down-regulationpharmacologymechanisms of actionmolecular pharmacologyneuropharmacologyreceptor (biochemistry)retromer complexaddiction biologymu opioid receptorsignal transductionneurosciencepharmacological research

Shining a Light on Orphan Gpcrs. Nature Chemical Biology (2026)

reflection removallightinglight regulationorphan gpcrslight science

Chemical Biology Approaches to Resolve the Subcellular Gpcr Signaling Landscape. Nature Chemical Biology (2025)

g protein-coupled receptorsignaling pathwaysbiochemical interactionbiomolecular interactionschemical biology approachescell signalingchemical biologymolecular cell biologymolecular biologybiological chemistrymolecular pathwayssignal transductionprotein sciencecellular biochemistrycell biology

Dnajc13 Localization to Endosomes is Opposed by Its J Domain and Its Disordered C-Terminus. Molecular Biology of the Cell (2025)

endocytic pathwaymolecular researchdnajc13 localizationprotein structurebiomolecular structuremolecular cell biologyj domainnucleic acidsmolecular biologystructural molecular biologystructural biologyprotein sciencedisordered c-terminuscell biology

Dnajc13 Regulates Gpcr Sorting at Endosomes (Abstract Id: 161875). Journal of Pharmacology and Experimental Therapeutics (2025)

endocytic pathwaymolecular sortingmolecular cell biologymolecular biologyabstract iddna replicationprotein sciencecellular biochemistrycell biology

Identification of Proteins Controlling Mu Opioid Receptor Recycling Using a Novel Chemical Biology Platform (Abstract Id: 157192). Journal of Pharmacology and Experimental Therapeutics (2025)

neuropeptide receptorsreceptorsdrug targetspharmacologypeptidesmechanisms of actionmolecular painprotein structureneuropharmacologychemical biologyreceptor (biochemistry)drug discoveryaddiction biologybiological chemistryabstract idprotein sciencepharmacological researchbiochemistry

Novel Fluorogenic Tool to Monitor Gpcr Expression, Downregulation, and Agonist-Induced Trafficking to the Lysosome (Abstract Id: 163959). Journal of Pharmacology and Experimental Therapeutics (2025)

g protein-coupled receptorendocytic pathwaycell traffickingcell signalingintracellular traffickingmolecular and cellular biologyclinical proteomicstherapeutic targetsmolecular cell biologyagonist-induced traffickingmolecular biologysecretory pathwaynovel fluorogenic toolsignal transductionmonitor gpcr expressioncellular biochemistrymolecular medicinecell biology

Real-Time Optical Control of Cb1 Receptor Signaling in Vitro With Tethered Photoswitchable (−)- Trans -Δ 9 -Tetrahydrocannabinol Derivatives. Journal of the American Chemical Society (2025)

optogeneticsphotoreceptor cellsphotochemistryphotomedicinebiophotonicstethered photoswitchablephotodynamic therapyreal-time optical controlsignal transductionbiochemistrycell biology

An Engineered Trafficking Biosensor Reveals a Role for Dnajc13 in Dor Downregulation. Nature Chemical Biology (2024)

Brandon NovyAleksandra DaguntsTatum WeishaarEmily E. HollandHayden AdoffEmily HutchinsonMonica De MariaMartin KampmannNikoleta G. TsvetanovaBraden T. Lobingier

biosensorsgene expressionenzyme inhibitiontranscription regulationintracellular traffickingmolecular regulationdor downregulationchemical biologybiomolecular engineeringengineered trafficking biosensormolecular biologydna repairprotein sciencesynthetic biologycrisprbiochemistry

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Braden Lobingier

Assistant Professor of Chemical Physiology and Biochemistry

Oregon Health & Science University

Affiliations

OHSU School of Medicine

Bob And Charlee Moore Institute For Nutrition And Wellness

Center Of The Amyloidosis

Division Of Cardiology

OGI School of Science and Engineering

Department Of Chemistry, Biochemistry And Molecular Biology

Department Of Physiology And Pharmacology

Oregon Health & Science University

Bob And Charlee Moore Institute For Nutrition And Wellness

School Of Medicine

Division Of Cardiology

School Of Medicine

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Braden Lobingier

Oregon Health & Science University

Assistant Professor of Chemical Physiology and Biochemistry

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Endosomal Sorting of the Glucagon-Like Peptide-1 Receptor (Glp-1R) is Controlled by the Retromer Complex (Abstract Id: 271201). Journal of Pharmacology and Experimental Therapeutics (2026)

g protein-coupled receptorreceptorspeptidespharmacological researchcell biology

Lysosomal Down-Regulation of the Mu Opioid Receptor is Opposed by the Retromer Complex. Science Advances (2026)

Shining a Light on Orphan Gpcrs. Nature Chemical Biology (2026)

reflection removallightinglight regulationorphan gpcrslight science

Chemical Biology Approaches to Resolve the Subcellular Gpcr Signaling Landscape. Nature Chemical Biology (2025)

Dnajc13 Localization to Endosomes is Opposed by Its J Domain and Its Disordered C-Terminus. Molecular Biology of the Cell (2025)

Dnajc13 Regulates Gpcr Sorting at Endosomes (Abstract Id: 161875). Journal of Pharmacology and Experimental Therapeutics (2025)

endocytic pathwaymolecular sortingmolecular cell biologymolecular biologyabstract iddna replicationprotein sciencecellular biochemistrycell biology

Identification of Proteins Controlling Mu Opioid Receptor Recycling Using a Novel Chemical Biology Platform (Abstract Id: 157192). Journal of Pharmacology and Experimental Therapeutics (2025)

Real-Time Optical Control of Cb1 Receptor Signaling in Vitro With Tethered Photoswitchable (−)- Trans -Δ 9 -Tetrahydrocannabinol Derivatives. Journal of the American Chemical Society (2025)

optogeneticsphotoreceptor cellsphotochemistryphotomedicinebiophotonicstethered photoswitchablephotodynamic therapyreal-time optical controlsignal transductionbiochemistrycell biology

An Engineered Trafficking Biosensor Reveals a Role for Dnajc13 in Dor Downregulation. Nature Chemical Biology (2024)

Brandon NovyAleksandra DaguntsTatum WeishaarEmily E. HollandHayden AdoffEmily HutchinsonMonica De MariaMartin KampmannNikoleta G. TsvetanovaBraden T. Lobingier

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