Faculty

Institution

Unit

Venue

Bin Liu

Professor

The University of Texas MD Anderson Cancer Center

Affiliations

Department Of Epigenetics And Molecular Carcinogenesis

MD Anderson UTHealth Houston Graduate School

Bin Liu is a Professor at The University of Texas MD Anderson Cancer Center. His research integrates cell biology, genetics, and molecular biology to address tumor biology, oncogene function, and cancer immunology. Recent work includes a Phase I trial of PRAME TCR-engineered IL15-transduced cord blood NK cells for refractory melanoma, IL-21 engineering enhancing NK activity against glioblastoma via CEBPD, and B-cell-specific Wwox deletion promoting plasmablastic tumors. He also investigates CDCA7’s DNA-binding domain in non-B DNA recognition, SAGA complex KAT module oncogenic programs in MYCN-amplified neuroblastoma, and age-specific mutant p53 induction in clonal hematopoiesis and acute myeloid leukemia.

Honors

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Bin Liu

The University of Texas MD Anderson Cancer Center

Professor

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genetics cell biology cancer research molecular biology tumor biology oncogenes gene expression oncology cancer biology cancer genomics cancer genetics pathology molecular cancer molecular cell biology cancer cells cell signaling genome biology cellular therapy carcinogenesis mammalian biology medicinal research genomics leukemia metastasis cancer discovery hematological malignancies cancer care virus research thoracic oncology gene function brain tumor research nucleic acids cancer growth disease gene identification cellular immune responses rna biology oncogenic agent immune dysregulation adaptive immune system bone research animal genetics gene characterization knockout mice cancer treatment cancer risk oral cancer salivary glands viral oncology molecular virology virus-host interactions pancreatic cancer rna-seq analysis expansive transcriptional network pancreatic cancer metastasis chromosomal rearrangements cytogenetics immune checkpoint inhibitors brain-immune interaction cancer immunosurveillance gene evolution embryonic development splicing variant prognosis functional genetic analysis gain-of-function activities oocyte-to-embryo transition erk-dependent dicer phosphorylation intron retentions prognostic impact glioblastoma subtypes gastroesophageal carcinoma cancer stem cells pan-bcl-2 inhibitor integrative genome analysis small nucleolar rnas unifying gene signature

Notable Scholarly Works

Notable Federal Grants

Collaborators

B-Cell–Specific Wwox Deletion Promotes Plasmablastic Tumor Development and Proinflammatory Signatures in Myeloma Model. Blood Neoplasia (2025)

tumor biologyhematological malignanciesmyeloma modelb-cell–specific wwox deletioncell biologycancer cellsoncogenesimmunologyplasmablastic tumor developmenttumor microenvironmentcell deathpathologymyeloid neoplasia

Phase I Dose Escalation and Expansion Study of Prame T-Cell Receptor (Tcr) Engineered Il15-Transduced Cord Blood–Derived Natural Killer (Nk) Cells in Patients With Recurrent and/or Refractory Melanoma (Prametime-Mel).. Journal of Clinical Oncology (2025)

immunomodulationcancer immunotherapyimmune responsescellular therapycell therapycell biologycancer cellsimmunotherapyexpansion studyimmunologycell researchcell transplantationnatural killerexperimental medicineprame t-cell receptorcellular immune responses

Age-Specific Induction of Mutant P53 Drives Clonal Hematopoiesis and Acute Myeloid Leukemia in Adult Mice. Cell Reports Medicine (2024)

hematologytumor biologyage-specific inductioncancer researchhaematopoiesishematological malignanciescell biologycancer cellsleukemiaoncogenesacute myeloid leukemiaadult micemyelopoiesiscell deathpathologymyeloid neoplasia

Author Correction: Kir-Based Inhibitory Cars Overcome Car-Nk Cell Trogocytosis-Mediated Fratricide and Tumor Escape. Nature Medicine (2024)

Ye LiRafet BasarGuohui WangEnli LiuJudy S. MoyesLi LiLucila N. KerbauyNadima UpretyMohsen FathiAli RezvanPinaki P. BanerjeeLuis Muniz-FelicianoTamara J. LaskowskiEmily EnsleyMay DaherMayra ShanleyMayela MendtSunil AcharyaBin LiuAlexander BiederstädtHind RafeiXingliang GuoLuciana Melo GarciaPaul LinSonny AngDavid MarinKen ChenLaura BoverRichard E. ChamplinNavin VaradarajanElizabeth J. ShpallKatayoun Rezvani

personalized medicinecancer immunotherapymedicinepharmacologycellular therapycancer researchauthor correctiononcogenic agentnon-pharmacological interventionsanti-cancer agentsbiological therapiestumor escapekir-based inhibitory carsherbal medicineimmunologynanomedicinemolecular medicinemedicinal researchpharmacological researchnature methodpharmacotherapy

Gene Expression Profile Analysis of Subregions of the Adult Female Reproductive Tract in the Brown Anole, Anolis Sagrei. Reproduction (2024)

female reproductive systembrown anolereproductive sciencegeneticsmolecular geneticsmorphology (biology)reproductive physiologyanolis sagreibiologyzoologyreproductive endocrinologymammalian biologyreproductive biology

Interleukin-21 Engineering Enhances Nk Cell Activity Against Glioblastoma via Cebpd. Cancer Cell (2024)

Mayra ShanleyMay DaherJinzhuang DouSufang LiRafet BasarHind RafeiMerve DedeJoy GuminJezreel Pantaleόn GarcίaAna Karen Nunez CortesShan HeCorry M. JonesSunil AcharyaNatalie W. FowlkesDonghai XiongSanjay SinghHila ShaimSamantha Claire HicksBin LiuAbhinav JainMohammad Fayyad ZamanQi MiaoYe LiNadima UpretyEnli LiuLuis Muniz-FelicianoGary M. DeyterVakul MohantyPatrick ZhangScott E. EvansElizabeth J. ShpallFrederick F. LangKen ChenKatayoun Rezvani

tumor biologycancer immunotherapycellular therapycancer researchcancer biologycancer cellsimmune checkpoint inhibitorsoncogenesbrain-immune interactionsystems biologyimmunologyvascular biologybrain tumor researchcancer immunosurveillancegliomasmolecular biologytumor microenvironmentcellular immune responses

Multifaceted Roles for Stat3 in Gammaherpesvirus Latency Revealed Through in Vivo B Cell Knockout Models. mBio (2024)

Chad H. HoganShana M. OwensGlennys V. ReynosoYifei LiaoThomas J. MeyerMonika A. ZelazowskaBin LiuXiaofan LiAnna K. GrosskopfCamille KhairallahVarvara KirillovNancy C. ReichBrian S. SheridanKevin M. McBrideBenjamin E. GewurzHeather D. HickmanJ. Craig ForrestLaurie T. Krug

virologygeneticsmolecular virologygene expressionhost responseviral geneticsgammaherpesvirus latencyviral oncologyimmunologyviral evolutionmolecular biologygeneral virologyvirus research

The Icf Syndrome Protein Cdca7 Harbors a Unique Dna Binding Domain That Recognizes a Cpg Dyad in the Context of a Non-B Dna. Science Advances (2024)

Swanand HardikarRen RenZhengzhou YingJujun ZhouJohn R. HortonMatthew D. BrambleBin LiuYue LuBigang LiuLuis Della ColettaJianjun ShenJiameng DanXing ZhangXiaodong ChengTaiping Chen

geneticsimmune dysregulationgene expressionnon-b dnamolecular biologyscience advancecpg dyad

The Kat Module of the Saga Complex Maintains the Oncogenic Gene Expression Program in Mycn- Amplified Neuroblastoma. Science Advances (2024)

tumor biologygene expressionmolecular cancergene regulationcell biologycancer cellsgene characterizationoncogenestranscription factorskat modulecell researchcancer discoverymolecular biologycarcinogenesissaga complex

B Cell-Intrinsic Stat3-Mediated Support of Latency and Interferon Suppression During Murine Gammaherpesvirus 68 Infection Revealed Through an in Vivo Competition Model. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Chad H. HoganShana M. OwensGlennys V. ReynosoVarvara KirillovThomas J. MeyerMonika A. ZelazowskaBin LiuXiaofan LiAniska ChikhalyaQiwen DongCamille KhairallahNancy C. ReichBrian SheridanKevin M. McBridePatrick HearingHeather D. HickmanJ. Craig ForrestLaurie T. Krug

virologyinfectious diseasesvirus-host interactionsimmunologyinterferon suppressionmolecular biologyvirus research

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Bin Liu

Professor

The University of Texas MD Anderson Cancer Center

Affiliations

Department Of Epigenetics And Molecular Carcinogenesis

MD Anderson UTHealth Houston Graduate School

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Bin Liu

The University of Texas MD Anderson Cancer Center

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

B-Cell–Specific Wwox Deletion Promotes Plasmablastic Tumor Development and Proinflammatory Signatures in Myeloma Model. Blood Neoplasia (2025)

Age-Specific Induction of Mutant P53 Drives Clonal Hematopoiesis and Acute Myeloid Leukemia in Adult Mice. Cell Reports Medicine (2024)

Author Correction: Kir-Based Inhibitory Cars Overcome Car-Nk Cell Trogocytosis-Mediated Fratricide and Tumor Escape. Nature Medicine (2024)

Gene Expression Profile Analysis of Subregions of the Adult Female Reproductive Tract in the Brown Anole, Anolis Sagrei. Reproduction (2024)

Interleukin-21 Engineering Enhances Nk Cell Activity Against Glioblastoma via Cebpd. Cancer Cell (2024)

Multifaceted Roles for Stat3 in Gammaherpesvirus Latency Revealed Through in Vivo B Cell Knockout Models. mBio (2024)

virologygeneticsmolecular virologygene expressionhost responseviral geneticsgammaherpesvirus latencyviral oncologyimmunologyviral evolutionmolecular biologygeneral virologyvirus research

The Icf Syndrome Protein Cdca7 Harbors a Unique Dna Binding Domain That Recognizes a Cpg Dyad in the Context of a Non-B Dna. Science Advances (2024)

Swanand HardikarRen RenZhengzhou YingJujun ZhouJohn R. HortonMatthew D. BrambleBin LiuYue LuBigang LiuLuis Della ColettaJianjun ShenJiameng DanXing ZhangXiaodong ChengTaiping Chen

geneticsimmune dysregulationgene expressionnon-b dnamolecular biologyscience advancecpg dyad

The Kat Module of the Saga Complex Maintains the Oncogenic Gene Expression Program in Mycn- Amplified Neuroblastoma. Science Advances (2024)

virologyinfectious diseasesvirus-host interactionsimmunologyinterferon suppressionmolecular biologyvirus research

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10 / page