Faculty

Institution

Unit

Venue

Aykut Uren

Georgetown University

Affiliations

School of Medicine

Biochemistry and Molecular & Cellular Biology

NoneAykut Uren is currently serving as a Biochemistry And Molecular & Cellular Biology faculty at Georgetown University.

Honors

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Experiences

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Education

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Aykut Uren

Georgetown University

You can click a keyword to filter the displayed items

oncology cancer research pharmacology cancer biology tumor biology molecular biology medicinal research genetics cancer treatment cell biology cancer care gene expression molecular cancer enzyme inhibition tumor targeting sarcoma oncogenes cancer genetics cancer genomics enzymes medicinal chemistry cancer cells protein science cellular therapy anti-cancer agents cell signaling cancer management biological chemistry cancer growth drug targeting thoracic oncology pharmacotherapy oncogenic agent cell regulation transcription regulation plasmonics mammalian biology cancer imaging rna biology vascular biology virus research cell death molecular virology gene regulation molecular regulation biomolecular interactions metastatic osteosarcoma protein expression clinical pharmacology pharmaceutical chemistry small molecule inhibitor transcriptional activity gene function viral oncology viral genetics cell cycle virus-host interactions cell motility hematological malignancies signaling pathways rna helicase alternative splicing sarcoma cells biological evaluation molecular interactions clinical medicine cutaneous biology cellular biology direct transcriptional target transgenic mice wnt action frizzled-related antagonist molecular cloning biphasic modulator inhibits growth tumor development

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 1093: Small Molecule Inhibitors of the Pax3:: Foxo1 Fusion Protein in Rhabdomyosarcoma. Cancer Research (2024)

Taryn ShawKay NakazawaPurushottam TiwariEryn NelsonJeffrey FormenChristian WolfJeffrey ToretskyAykut Üren

medicinal chemistrypharmacologymolecular cancercancer treatmentcancer biologytumor targetingcancer researchoncologyenzyme inhibitionradiation oncologydrug targetinganti-cancer agentsclinical researchmedicinal researchsmall molecule inhibitorscancer caretherapeutic targets

Abstract 1560: In Vivo Crispr/Cas9 Transcriptional Activation Screen Leads to Discovery of Inafm2, a Novel Driver of Metastasis. Cancer research (2024)

Anna MolotkovaEmre DenizMatthew SwiftEric GlasgowJeffrey ToretskyAykut Üren

transcriptional activation screencancer cellsgeneticscancer biologymolecular cancercancer researchcancer genomicsmetastasistumor biologycancer treatmentgene expressiononcologycancer geneticscancer carecrisprcancer discoveryradiation oncologymolecular biologymedicinal researchnovel driver

Abstract B076: Rome, a Novel Membrane Protein in Vertebrates, Enhances Metastatic Phenotype of Ewing Sarcoma Cells. Cancer Research (2024)

Anna MolotkovaEmre DenizMatthew SwiftEric GlasgowJeffrey ToretskyAykut Uren

cancer biologycancer researchmolecular biologymembrane proteinssarcomasarcoma cells

Anticancer Drugs of Lysine Specific Histone Demethylase-1 (Lsd1) Display Variable Inhibition on Nucleosome Substrates. Biochemistry (2024)

Dulmi SenanayakaDanyun ZengEmre DenizIndunil K. PriyankaraJoceline HelmbreckOwen SchneiderAashay MardikarAykut UrenNicholas J. Reiter

pharmacologybiochemistrymolecular biologyanticancer drugsenzymesnucleosome substrates

CORRECTION: Yk-4-279 Effectively Antagonizes Ews-Fli1 Induced Leukemia in a Transgenic Mouse Model. Oncotarget (2024)

Tsion Zewdu MinasJenny HanTahereh JavaheriSung-Hyeok HongMichaela SchledererYasemin Saygideğer-KontHaydar ÇelikKristina M. MuellerIdil TemelMetin ÖzdemirliHeinrich KovarHayriye Verda ErkizanJeffrey ToretskyLukas KennerRichard MorigglAykut Üren

geneticsoncologyleukemiacancer geneticstransgenic mouse model

Indolent Cd4+ Car T-Cell Lymphoma After Cilta-Cel Car T-Cell Therapy. New England Journal of Medicine (2024)

Metin OzdemirliThomas M LoughneyEmre DenizJoeffrey J ChahineMaher AlbitarStefania PittalugaSam SadighPhilippe ArmandAykut UrenKenneth C Anderson

cancer immunotherapymedicineclinical transplantationlymphoid neoplasiacancer researchoncologypharmacotherapycellular therapyimmunologydermatologyimmunotherapymedicinal researchcell therapyhematologyclinical immunology

The Pax Genes: Roles in Development, Cancer, and Other Diseases. Cancers (2024)

Taryn ShawFrederic G BarrAykut Üren

geneticsurologycancer biologymolecular cancerpax genesother diseasescancer researchoncologymolecular evidencetumor biologyveterinary medicinecarcinogenesiscell biology

Data From Identification of Novel Ezrin Inhibitors Targeting Metastatic Osteosarcoma by Screening Open Access Malaria Box. (2023)

Haydar ÇelikSung-Hyeok HongDaisy D. Colón-LópezJenny HanYasemin Saygideger KontTsion Z. MinasMatthew SwiftMikell PaigeEric GlasgowJeffrey A. ToretskyJürgen BoschAykut Üren

cancer managementpharmacologymalariadrug discoverycancer researchoncologydrug targetingdrug developmentimmunologydermatologymedicinal researchnovel therapieslead identificationmetastatic osteosarcoma

Data From Stress-Mediated Reprogramming of Prostate Cancer One-Carbon Cycle Drives Disease Progression. (2023)

Nora PällmannKe DengMarte LivgårdMartina TesikovaYixin JinNicolai Sebastian FrengenNermin KahramanHamada M. MokhlisBulent OzpolatWanja KildalHavard Emil DanielsenLadan FazliPaul S. RenniePartha P. BanerjeeAykut ÜrenYang JinOmer F. KuzuFahri Saatcioglu

neurologyurologycancer biologyhealth sciencescancer researchoncologyredox biologytumor biologystress-mediated reprogrammingprostate cancer

Design, Synthesis and Biological Evaluation of Nucleosidic Cd99 Inhibitors That Selectively Reduce Ewing Sarcoma Viability. European Journal of Medicinal Chemistry (2023)

Kaluvu BalaramanEmre DenizEryn NelsonSamantha L. PilicerSezen AtasoyAnna MolotkovaHandan SevimPurushottam B. TiwariAykut ÜrenChristian Wolf

medicinal chemistrypharmacologyhistocompatibilityhealth sciencesmedicinedrug discoveryoncologyclinical chemistrypharmaceutical chemistryenzyme inhibitionpharmaceutical sciencesdrug deliverypharmacotherapyanti-cancer agentstherapeutic efficacytumor biologysarcoma viabilitybiological evaluation

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Aykut Uren

Georgetown University

Affiliations

School of Medicine

Biochemistry and Molecular & Cellular Biology

NoneAykut Uren is currently serving as a Biochemistry And Molecular & Cellular Biology faculty at Georgetown University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Aykut Uren

Georgetown University

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 1093: Small Molecule Inhibitors of the Pax3:: Foxo1 Fusion Protein in Rhabdomyosarcoma. Cancer Research (2024)

Taryn ShawKay NakazawaPurushottam TiwariEryn NelsonJeffrey FormenChristian WolfJeffrey ToretskyAykut Üren

Abstract 1560: In Vivo Crispr/Cas9 Transcriptional Activation Screen Leads to Discovery of Inafm2, a Novel Driver of Metastasis. Cancer research (2024)

Anna MolotkovaEmre DenizMatthew SwiftEric GlasgowJeffrey ToretskyAykut Üren

Abstract B076: Rome, a Novel Membrane Protein in Vertebrates, Enhances Metastatic Phenotype of Ewing Sarcoma Cells. Cancer Research (2024)

Anna MolotkovaEmre DenizMatthew SwiftEric GlasgowJeffrey ToretskyAykut Uren

cancer biologycancer researchmolecular biologymembrane proteinssarcomasarcoma cells

Anticancer Drugs of Lysine Specific Histone Demethylase-1 (Lsd1) Display Variable Inhibition on Nucleosome Substrates. Biochemistry (2024)

Dulmi SenanayakaDanyun ZengEmre DenizIndunil K. PriyankaraJoceline HelmbreckOwen SchneiderAashay MardikarAykut UrenNicholas J. Reiter

pharmacologybiochemistrymolecular biologyanticancer drugsenzymesnucleosome substrates

CORRECTION: Yk-4-279 Effectively Antagonizes Ews-Fli1 Induced Leukemia in a Transgenic Mouse Model. Oncotarget (2024)

geneticsoncologyleukemiacancer geneticstransgenic mouse model

Indolent Cd4+ Car T-Cell Lymphoma After Cilta-Cel Car T-Cell Therapy. New England Journal of Medicine (2024)

Metin OzdemirliThomas M LoughneyEmre DenizJoeffrey J ChahineMaher AlbitarStefania PittalugaSam SadighPhilippe ArmandAykut UrenKenneth C Anderson

The Pax Genes: Roles in Development, Cancer, and Other Diseases. Cancers (2024)

Taryn ShawFrederic G BarrAykut Üren

geneticsurologycancer biologymolecular cancerpax genesother diseasescancer researchoncologymolecular evidencetumor biologyveterinary medicinecarcinogenesiscell biology

Data From Identification of Novel Ezrin Inhibitors Targeting Metastatic Osteosarcoma by Screening Open Access Malaria Box. (2023)

Haydar ÇelikSung-Hyeok HongDaisy D. Colón-LópezJenny HanYasemin Saygideger KontTsion Z. MinasMatthew SwiftMikell PaigeEric GlasgowJeffrey A. ToretskyJürgen BoschAykut Üren

cancer managementpharmacologymalariadrug discoverycancer researchoncologydrug targetingdrug developmentimmunologydermatologymedicinal researchnovel therapieslead identificationmetastatic osteosarcoma

Data From Stress-Mediated Reprogramming of Prostate Cancer One-Carbon Cycle Drives Disease Progression. (2023)

neurologyurologycancer biologyhealth sciencescancer researchoncologyredox biologytumor biologystress-mediated reprogrammingprostate cancer

Design, Synthesis and Biological Evaluation of Nucleosidic Cd99 Inhibitors That Selectively Reduce Ewing Sarcoma Viability. European Journal of Medicinal Chemistry (2023)

Kaluvu BalaramanEmre DenizEryn NelsonSamantha L. PilicerSezen AtasoyAnna MolotkovaHandan SevimPurushottam B. TiwariAykut ÜrenChristian Wolf

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