Avadhesh Sharma

Philadelphia College of Osteopathic Medicine

Affiliations

School of Pharmacy

Department Of Pharmacy Practice

Philadelphia College of Osteopathic Medicine

Department Of Pharmacy Practice

School Of Pharmacy

NoneAvadhesh Sharma is currently serving as a Pharmacy Practice faculty at Philadelphia College of Osteopathic Medicine.

Honors

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Experiences

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Education

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Avadhesh Sharma

Philadelphia College of Osteopathic Medicine

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inflammation immunology health sciences physiology cell death apoptosis medicine cardiovascular disease oxidative stress pathogenic bacteria sepsis ageing membrane biology respiratory medicine experimental medicine intensive care resuscitation cardiovascular research molecular physiology vascular biology oral health oral biology oral medicine experimental gerontology experimental biology mitochondrial function mitochondrial dynamics myocardial infarction fibrosis mitochondrial biogenesis biogerontology acute lung injury severe polymicrobial sepsis myocardial mitochondrial mechanisms apoptosis markers age-dependent differential expression gingival tissue lipopolysaccharide-induced hypotension

Notable Scholarly Works

Notable Federal Grants

Collaborators

Immune Complex-Induced, Nitric Oxide-Mediated Vascular Endothelial Cell Death by Phagocytes is Prevented With Decoy Fcγreceptors. PLoS ONE (2016)

C Urrent Opinion Targeting the Immune System to Treat Hypertension: Where Are We?. (2014)

Targeting the Immune System to Treat Hypertension. Current Opinion in Nephrology & Hypertension (2014)

Primary Human Cardiomyocyte Culture: A Model for Assessment of Cardiovascular Disorders. The FASEB Journal (2013)

Naloxone Reverses Thrombin‐Induced Increase in Txb2 in Patients Treated With Subtherapeutic Dose of Ketamine During Wisdom Teeth Extraction. The FASEB Journal (2012)

Mechanisms Involved in Apoptosis Events Contributing to Sepsis-Induced Myocardial Dysfunction. Current Drug Therapy (2011)

Modulation of Myocardial Mitochondrial Mechanisms During Severe Polymicrobial Sepsis in the Rat. PLoS ONE (2011)

Mani ChopraHoney B. GoldenSrinivas MullapudiWilliam DowhanDavid E. DostalAvadhesh C. Sharma

pathogenic bacteriasevere polymicrobial sepsisoxidative stressfibrosisintensive caremolecular physiologymyocardial infarctionvascular biologycardiovascular diseasemitochondrial biogenesisinflammationinfectious diseasescardiovascular researchmyocardial mitochondrial mechanismsimmunologyresuscitationmitochondrial dynamicsmitochondrial functionsepsisphysiology

Caspase‐3 Knock‐Down Reverses Contractile Dysfunction Induced by Sepsis in Adult Rat Ventricular Myocytes. British Journal of Pharmacology (2010)

Modulation of Myocardial Mitochondrial Vdac/Mitok Atp Channels in Sepsis. The FASEB Journal (2010)

Norepinephrine Decreases Ejection Fraction and Downregulates Sepsis‐Induced Elevated Antiapoptotic Genes in a Hyperdynamic Polymicrobial Septic Rat Model. The FASEB Journal (2010)