Faculty

Institution

Unit

Venue

Arun Sreekumar

Professor

Baylor College of Medicine

Affiliations

Baylor College of Medicine Research

Arun Sreekumar is currently serving as a Baylor College Of Medicine Research Professor at Baylor College of Medicine.

Honors

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Experiences

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Education

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Arun Sreekumar

Baylor College of Medicine

Professor

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cancer research cancer biology oncology urology prostate cancer tumor biology molecular biology medicinal research breast cancer molecular cancer metabolomics cell biology systems biology cancer genetics gene expression cancer care oncogenes prostatic disease cancer genomics proteomics cancer cells cancer discovery redox biology metabolomic profiling protein science metabolic profiling cancer treatment molecular metabolism cell metabolism clinical investigation cancer disparities tumor targeting protein microarrays molecular physiology enzyme inhibition metabolic regulation pathway analysis cancer risk endocrine-related cancers prostate cancer progression signaling pathways mitochondrial function breast oncology microarray data analysis cell regulation prostate cancer cells molecular cell biology cellular physiology leukemia rna biology endocrine oncology clinical evidence humoral response clinical medicine cancer growth disease progression gene function cell physiology lymphoid neoplasia biomarker (medicine) in vivo systems neurochemistry andrology triple-negative breast cancer castration-resistant prostate cancer clinical stages urothelial cancer african americans phenolic substrates molecular dynamics transcriptional elongation mutual regulation immunostimulatory reprogramming breast cancer prognosis circadian homeostasis chromatin modification drug metabolism drug resistance metabolic remodeling pharmacology signal transduction drug resistance mechanisms

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract C078: Delineating the Role of the Homocysteine-Folate-Tyms Axis and Uracil Accumulation in African American Prostate Cancer Patients. Cancer Epidemiology Biomarkers & Prevention (2025)

benign prostatic hyperplasiauracil accumulationabstract c078radiation oncologycancer researchmolecular cancerurologyprostatic diseaseoncologycancer cellshomocysteine-folate-tyms axisprostate cancer

Parp Inhibitor Response is Enhanced in Prostate Cancer When Xrcc1 Expression is Reduced. NAR Cancer (2025)

Kaveri GoelVani VenkatappaKimiko L KriegerDongquan ChenArun SreekumarNatalie R Gassman

gene expressionparp inhibitor responsecancer researchtumor biologyurologyprostatic diseasemolecular biologyoncologycancer biologyprostate cancer

Abstract 6692: Intermittent Fasting-Remodeled Gut Microbiota Improves Anti-Tumor Immunity in Pancreatic Cancer. Cancer Research (2024)

Le LiVidhi ChandraOlivereen Le RouxRian Morgan HowellVirginia TahanNagireddy PutluriJoseph PetrosinoArun SreekumarJay K. KollsJames WhiteFlorencia McAllister

immunologymicrobiomegut microbesanti-tumor immunitycancer carecancer managementcancer researchpancreatic cancercancer immunotherapycancer preventiononcologyglobal healthimmune responsescancer treatmentcancer biologyhealth sciences

Abstract Po2-14-11: Proteogenomic Approaches for the Identification of Nf1/Neurofibromin-Depleted Estrogen Receptor Positive Breast Cancers for Targeted Treatment. Cancer Research (2024)

Beom-Jun KimZe-Yi ZhengJonathan LeiMatthew HoltAnran ChenJianheng PengDiana FandinoPurba SinghHilda KennedyYongchao DouM Rosario Chica-ParradoEmmanuel BikorimanaDan YeYunguan WangAriella HankerNada MohamedSusan HilsenbeckBora LimJaya Ruth AsirvathamArun SreekumarBing ZhangGeorge MilesMeenakshi AnuragMatthew EllisEric Chang

tumor targetingtargeted treatmentbiomarker targetproteomicscancer researchproteome researchnovel therapiescancer discoverytherapeutic targetsmolecular biologybreast canceroncologycancer treatmentcancer biology

Integrative Spatial Omics Reveals Distinct Tumor-Promoting Multicellular Niches and Immunosuppressive Mechanisms in African American and European American Patients With Tnbc. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Qian ZhuAkhila BalasubramanianJaya Ruth AsirvathamBadrajee PiyarathnaJaspreet KaurNada MohamedLing WuMegha ChatterjeeStacy WangNiloufar PourfarrokhUttam RasailyYitian XuJunjun ZhengDeborah JebakumarArundathi RaoShu-hsia ChenYi LiEric ChangXiaoxian LiRitu AnejaXiang H.-F. ZhangArun Sreekumar

tumor heterogeneitytherapeutic efficacytumor targetingcancer caremolecular cancercancer biologyimmunosuppressive mechanismsdermatologycancer researchtumor suppressorscancer immunotherapyafrican american studiestumor biologyimmunologygene expressioncancer imagingoncologymedicinal researchcellular therapy

Mitochondrial Reprogramming by Activating Oxphos via Glutamine Metabolism in African American Patients With Bladder Cancer. JCI Insight (2024)

Karthik Reddy Kami ReddyDanthasinghe Waduge Badrajee PiyarathnaJun Hyoung ParkVasanta PutluriChandra Sekhar AmaraAbu Hena Mostafa KamalJun XuDaniel KraushaarShixia HuangSung Yun JungLivia S EberlinJabril R JohnsonRick A KittlesLeomar Y BallesterKrishna ParsawarM Minhaj SiddiquiJianjun GaoAdriana Langer GramerRoni J BollagMartha K TerrisYair LotanChad J CreightonSeth P LernerArun SreekumarBenny Abraham KaipparettuNagireddy Putluri

african american patientsmitochondrial reprogrammingbladder cancerglutamine metabolism

The Il6/Jak/Stat3 Signaling Axis is a Therapeutic Vulnerability in Smarcb1-Deficient Bladder Cancer. Nature Communications (2024)

Chandra Sekhar AmaraKarthik Reddy Kami ReddyYang YuntaoYuen San ChanDanthasinghe Waduge Badrajee PiyarathnaLacey Elizabeth DobroleckiDavid J. H. ShihZhongcheng ShiJun XuShixia HuangMatthew J. EllisAndrea B. ApoloLeomar Y. BallesterJianjun GaoDonna E. HanselYair LotanH. Courtney HodgesSeth P. LernerChad J. CreightonArun SreekumarW. Jim ZhengPavlos MsaouelShyam M. KavuriNagireddy Putluri

signaling pathwaysdisease progressionbladder cancersystems biologymolecular cancerurologymolecular biologycancer biologytumor biologytherapeutic vulnerability

Abstract 6114: Race-Associated Base Excision Repair Defects Alter the Dna Damage Landscape in Prostate Cancer. Cancer Research (2023)

Kaveri GoelKimiko KriegerManoj SonavaneArun SreekumarNatalie R. Gassman

neurologycancer careradiation oncologycancer researchtumor biologyurologysurgical oncologydna damage landscapecancer imagingoncologycancer treatmentdna repaircancer biologyprostate cancer

Author Correction: Histone H2A Lys130 Acetylation Epigenetically Regulates Androgen Production in Prostate Cancer. Nature Communications (2023)

Thanh NguyenDhivya SridaranSurbhi ChouhanCody WeimholtAudrey WilsonJingqin LuoTiandao LiJohn KoomenBin FangNagireddy PutluriArun SreekumarFelix Y. FengKiran MahajanNupam P. Mahajan

neurologycancer geneticscell regulationhuman geneticscancer researchepigenetic changesandrogen productiongeneticsurologyoncologymedicinal researchepigeneticsmedical geneticscancer biologyprostate cancerauthor correction

Conjugated Bile Acids Are Nutritionally Re-Programmable Antihypertensive Metabolites. Journal of Hypertension (2023)

Saroj ChakrabortyAnju LullaXi ChengJi-Youn YeoJuthika MandalTao YangXue MeiPiu SahaRachel M. GolonkaBeng San YeohBlair MellWei JiaVasanta PutluriDanthasinghe Waduge Badrajee PiyarathnaNagireddy PutluriArun SreekumarKatie MeyerMatam Vijay-KumarBina Joe

physiologycardiologymedicinal chemistrypharmacologydrug metabolismhypertensionre-programmable antihypertensive metabolitesantihypertensive therapybile acidsnutritional biochemistryhealth sciences

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Arun Sreekumar

Professor

Baylor College of Medicine

Affiliations

Baylor College of Medicine Research

Arun Sreekumar is currently serving as a Baylor College Of Medicine Research Professor at Baylor College of Medicine.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Arun Sreekumar

Baylor College of Medicine

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract C078: Delineating the Role of the Homocysteine-Folate-Tyms Axis and Uracil Accumulation in African American Prostate Cancer Patients. Cancer Epidemiology Biomarkers & Prevention (2025)

benign prostatic hyperplasiauracil accumulationabstract c078radiation oncologycancer researchmolecular cancerurologyprostatic diseaseoncologycancer cellshomocysteine-folate-tyms axisprostate cancer

Parp Inhibitor Response is Enhanced in Prostate Cancer When Xrcc1 Expression is Reduced. NAR Cancer (2025)

Kaveri GoelVani VenkatappaKimiko L KriegerDongquan ChenArun SreekumarNatalie R Gassman

gene expressionparp inhibitor responsecancer researchtumor biologyurologyprostatic diseasemolecular biologyoncologycancer biologyprostate cancer

Abstract 6692: Intermittent Fasting-Remodeled Gut Microbiota Improves Anti-Tumor Immunity in Pancreatic Cancer. Cancer Research (2024)

Le LiVidhi ChandraOlivereen Le RouxRian Morgan HowellVirginia TahanNagireddy PutluriJoseph PetrosinoArun SreekumarJay K. KollsJames WhiteFlorencia McAllister

Abstract Po2-14-11: Proteogenomic Approaches for the Identification of Nf1/Neurofibromin-Depleted Estrogen Receptor Positive Breast Cancers for Targeted Treatment. Cancer Research (2024)

Mitochondrial Reprogramming by Activating Oxphos via Glutamine Metabolism in African American Patients With Bladder Cancer. JCI Insight (2024)

african american patientsmitochondrial reprogrammingbladder cancerglutamine metabolism

The Il6/Jak/Stat3 Signaling Axis is a Therapeutic Vulnerability in Smarcb1-Deficient Bladder Cancer. Nature Communications (2024)

signaling pathwaysdisease progressionbladder cancersystems biologymolecular cancerurologymolecular biologycancer biologytumor biologytherapeutic vulnerability

Abstract 6114: Race-Associated Base Excision Repair Defects Alter the Dna Damage Landscape in Prostate Cancer. Cancer Research (2023)

Kaveri GoelKimiko KriegerManoj SonavaneArun SreekumarNatalie R. Gassman

neurologycancer careradiation oncologycancer researchtumor biologyurologysurgical oncologydna damage landscapecancer imagingoncologycancer treatmentdna repaircancer biologyprostate cancer

Author Correction: Histone H2A Lys130 Acetylation Epigenetically Regulates Androgen Production in Prostate Cancer. Nature Communications (2023)

Thanh NguyenDhivya SridaranSurbhi ChouhanCody WeimholtAudrey WilsonJingqin LuoTiandao LiJohn KoomenBin FangNagireddy PutluriArun SreekumarFelix Y. FengKiran MahajanNupam P. Mahajan

Conjugated Bile Acids Are Nutritionally Re-Programmable Antihypertensive Metabolites. Journal of Hypertension (2023)

physiologycardiologymedicinal chemistrypharmacologydrug metabolismhypertensionre-programmable antihypertensive metabolitesantihypertensive therapybile acidsnutritional biochemistryhealth sciences

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