Faculty

Institution

Unit

Venue

Arthur R. Salomon

Professor of Molecular Biology Cell Biology and Biochemistry Professor of Chemistry Professor of Medical Science Professor of Pediatrics Professor of Molecular Biology Cell Biology and Biochemistry Research

Brown University

Affiliations

Department of Chemistry

Warren Alpert Medical School

Molecular Biology, Cell Biology, & Biochemistry

Arthur R. Salomon is currently serving as a Chemistry Professor of Molecular Biology Cell Biology and Biochemistry Professor of Chemistry Professor of Medical Science Professor of Pediatrics Professor of Molecular Biology Cell Biology and Biochemistry Research at Brown University.

Honors

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Experiences

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Education

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Arthur R. Salomon

Brown University

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immunology proteomics cell biology cell signaling pharmacology molecular biology signal transduction membrane biology protein science medicinal research cell regulation enzymes protein phosphorylation signaling pathways tumor biology mass spectrometry mammalian biology molecular physiology protein function molecular regulation analytical chemistry enzyme inhibition biological chemistry redox biology liver physiology cancer biology pathway analysis molecular cell biology molecular immunology apoptosis adaptive immune system mitochondrial function animal physiology proteome research cell death receptor tyrosine kinases enzyme catalysis tyrosine phosphoproteome quantitative proteomic data t-cell receptor phosphoproteomic analysis mitochondrial respiration cell metabolism clinical chemistry drug analysis molecular science cell proliferation protein mass spectrometry immunochemistry host specificity enzyme specificity host factors drug targeting mechanisms of action functional selectivity rational drug design mammalian physiology translational proteomics proteomic technologies cell culture catalyst activation liquid chromatography cell cycle relational database secretory pathway tumor cell glycogen tyrosine phosphorylation pathways robust phosphoproteomic profiling tandem mass spectrometry tyrosine phosphorylation sites camp-dependent tyrosine phosphorylation mechanistic basis polyketide inhibitors old enzyme protein phosphorylation sites protein disruption clinical proteomics systems biology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Deep Phosphotyrosine Characterisation of Primary Murine T Cells Using Broad Spectrum Optimisation of Selective Triggering. PROTEOMICS (2024)

Aurora CallahanXien Yu ChuaAlijah A. GriffithTobias HildebrandtGuoping FuMengzhou HuRenren WenArthur R. Salomon

immunologypharmacologydeep phosphotyrosine characterisationdeep learningbroad spectrum optimisationbiological imagingt-regulatory celltissue imagingselective triggeringprotein scienceneuroscience

Gab3 Plays an Essential Role in Cd8 + T-Cell Expansion Through Regulating Il-2-Mediated Activation of Pi3K/Akt/Mtor and Erk/Foxo Pathways. Blood (2023)

Guoping FuYongwei ZhengGang XinZhengqi WangKevin D. BuntingWeiguo CuiArthur SalomonRenren Wen

immunologysignaling pathwaysmedicinegene expressioninsulin signalinghematologycellular immune responsescell signalingessential roleadaptive immune systemimmune responsessignal transductioncell regulationliver physiologycell biology

Mouse Primary T Cell Phosphotyrosine Proteomics Enabled by Boost. bioRxiv (Cold Spring Harbor Laboratory) (2022)

Xien Yu ChuaKenneth P. CallahanAlijah A. GriffithTobias HildebrandtGuoping FuMengzhou HuRenren WenArthur R. Salomon

immunologyproteomicscell biology

Silac Phosphoproteomics Reveals Unique Signaling Circuits in Car-T Cells and the Inhibition of B Cell-Activating Phosphorylation in Target Cells. Journal of Proteome Research (2022)

Alijah A. GriffithKenneth P. CallahanNathan Gordo KingQian XiaoXiaolei SuArthur R. Salomon

signaling pathwaysproteomicspharmacologytarget cellscell signalingmedicinal researchcar-t cellssignal transductionneurosciencecell biology

Ovalbumin Antigen-Specific Activation of Human T Cell Receptor Closely Resembles Soluble Antibody Stimulation as Revealed by Boost Phosphotyrosine Proteomics. Journal of Proteome Research (2021)

Xien Yu ChuaArthur Salomon

immunologyproteomicspharmacologyovalbumin antigen-specific activationsoluble antibody stimulationcell biology

Quantitative Interactomics of Lck-Turboid in Living Human T Cells Unveils T Cell Receptor Stimulation-Induced Proximal Lck Interactors. Journal of Proteome Research (2020)

Xien Yu ChuaTimothy AballoWilliam ElnemerMelanie TranArthur Salomon

immunologybiomolecular interactionsproteomicsinteractomicsquantitative interactomicscell interactionsadaptive immune systemimmune responsesmembrane biologymedicinal researchprotein scienceneurosciencebrain-immune interactioncell biology

Tandem Mass Tag Approach Utilizing Pervanadate Boost Channels Delivers Deeper Quantitative Characterization of the Tyrosine Phosphoproteome. Molecular & Cellular Proteomics (2020)

Xien Yu ChuaTheresa MensahTimothy AballoSamuel G. MackintoshRicky D. EdmondsonArthur R. Salomon

proteomicspharmacologybiological engineeringtyrosine phosphoproteomemolecular biologyquantitative characterizationprotein sciencemembrane biology

Regulation of Respiration and Apoptosis by Cytochrome C Threonine 58 Phosphorylation. Scientific Reports (2019)

Junmei WanHasini A. KalpageAsmita VaishnavJenney LiuIcksoo LeeGargi MahapatraAlice A. TurnerMatthew P. ZurekQinqin JiCarlos T. MoraesMaurice-Andre RecanatiLawrence I. GrossmanArthur R. SalomonBrian F. P. EdwardsMaik Hüttemann

cell deathprotein phosphorylationapoptosismolecular biologycell regulationmembrane biology

Serine‐47 Phosphorylation of Cytochrome C in the Mammalian Brain Regulates Cytochrome C Oxidase and Caspase‐3 Activity. The FASEB Journal (2019)

Hasini A. KalpageAsmita VaishnavJenney LiuAshwathy VarugheseJunmei WanAlice A. TurnerQinqin JiMatthew P. ZurekAlexandr A. KapralovValerian E. KaganJoseph S. BrunzelleMaurice‐Andre RecanatiLawrence I. GrossmanThomas H. SandersonIcksoo LeeArthur R. SalomonBrian F. P. EdwardsMaik Hüttemann

mammalian biologyneuroscienceneuroanatomymammalian brain

Fibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis. Cell Metabolism (2018)

Marion CurtisHilary A. KennyBradley AshcroftAbir MukherjeeAlyssa JohnsonYilin ZhangYnes HelouRaquel BatlleXiaojing LiuNuria GutierrezXia GaoS. Diane YamadaRicardo LastraAnthony MontagNagib AhsanJason W. LocasaleArthur R. SalomonAngel R. NebredaErnst Lengyel

metastasiscancer researchtumor cell glycogencell proliferationcell biologycancer biologytumor biologycell metabolism

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Arthur R. Salomon

Brown University

Affiliations

Department of Chemistry

Warren Alpert Medical School

Molecular Biology, Cell Biology, & Biochemistry

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Arthur R. Salomon

Brown University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Deep Phosphotyrosine Characterisation of Primary Murine T Cells Using Broad Spectrum Optimisation of Selective Triggering. PROTEOMICS (2024)

Aurora CallahanXien Yu ChuaAlijah A. GriffithTobias HildebrandtGuoping FuMengzhou HuRenren WenArthur R. Salomon

immunologypharmacologydeep phosphotyrosine characterisationdeep learningbroad spectrum optimisationbiological imagingt-regulatory celltissue imagingselective triggeringprotein scienceneuroscience

Gab3 Plays an Essential Role in Cd8 + T-Cell Expansion Through Regulating Il-2-Mediated Activation of Pi3K/Akt/Mtor and Erk/Foxo Pathways. Blood (2023)

Guoping FuYongwei ZhengGang XinZhengqi WangKevin D. BuntingWeiguo CuiArthur SalomonRenren Wen

Mouse Primary T Cell Phosphotyrosine Proteomics Enabled by Boost. bioRxiv (Cold Spring Harbor Laboratory) (2022)

Xien Yu ChuaKenneth P. CallahanAlijah A. GriffithTobias HildebrandtGuoping FuMengzhou HuRenren WenArthur R. Salomon

immunologyproteomicscell biology

Silac Phosphoproteomics Reveals Unique Signaling Circuits in Car-T Cells and the Inhibition of B Cell-Activating Phosphorylation in Target Cells. Journal of Proteome Research (2022)

Alijah A. GriffithKenneth P. CallahanNathan Gordo KingQian XiaoXiaolei SuArthur R. Salomon

signaling pathwaysproteomicspharmacologytarget cellscell signalingmedicinal researchcar-t cellssignal transductionneurosciencecell biology

Ovalbumin Antigen-Specific Activation of Human T Cell Receptor Closely Resembles Soluble Antibody Stimulation as Revealed by Boost Phosphotyrosine Proteomics. Journal of Proteome Research (2021)

Xien Yu ChuaArthur Salomon

immunologyproteomicspharmacologyovalbumin antigen-specific activationsoluble antibody stimulationcell biology

Quantitative Interactomics of Lck-Turboid in Living Human T Cells Unveils T Cell Receptor Stimulation-Induced Proximal Lck Interactors. Journal of Proteome Research (2020)

Xien Yu ChuaTimothy AballoWilliam ElnemerMelanie TranArthur Salomon

Tandem Mass Tag Approach Utilizing Pervanadate Boost Channels Delivers Deeper Quantitative Characterization of the Tyrosine Phosphoproteome. Molecular & Cellular Proteomics (2020)

Xien Yu ChuaTheresa MensahTimothy AballoSamuel G. MackintoshRicky D. EdmondsonArthur R. Salomon

proteomicspharmacologybiological engineeringtyrosine phosphoproteomemolecular biologyquantitative characterizationprotein sciencemembrane biology

Regulation of Respiration and Apoptosis by Cytochrome C Threonine 58 Phosphorylation. Scientific Reports (2019)

cell deathprotein phosphorylationapoptosismolecular biologycell regulationmembrane biology

Serine‐47 Phosphorylation of Cytochrome C in the Mammalian Brain Regulates Cytochrome C Oxidase and Caspase‐3 Activity. The FASEB Journal (2019)

mammalian biologyneuroscienceneuroanatomymammalian brain

Fibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis. Cell Metabolism (2018)

metastasiscancer researchtumor cell glycogencell proliferationcell biologycancer biologytumor biologycell metabolism

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4
5
8
10 / page

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molecular biology

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molecular informatics

proteomic technologies

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interactomics

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molecular biology

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