Faculty

Institution

Unit

Venue

Ann Harris

Professor

Case Western Reserve University

Affiliations

School of Medicine

Genetics and Genome Sciences

Ann Harris is currently serving as a Genetics And Genome Sciences Professor at Case Western Reserve University.

Honors

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Experiences

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Education

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Ann Harris

Case Western Reserve University

Professor

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genetics molecular biology cell biology gene expression human genetics cystic fibrosis membrane biology molecular genetics gene regulation genomics genome biology medical genetics molecular and cellular biology molecular cell biology molecular physiology transcription regulation pharmacology cellular physiology gene therapy molecular regulation mammalian biology gene function cellular biology medicinal research respiratory medicine cell regulation liver physiology cell research biochemical sciences cancer biology nucleic acids vascular biology cancer cells protein science rna biology cftr gene cell culture signaling pathways cytogenetics epithelial cells cystic fibrosis gene cftr expression molecular cancer gene regulatory networks gene editing developmental genetics protein genetics cancer genetics animal genetics biological chemistry cell physiology biochemical genetics mutagenesis tissue physiology cancer genomics fibrosis disease gene identification pathway analysis physiological research membrane transport human epididymis host genetics colorectal cancer in vivo systems knockout mice cftr gene expression cftr locus collagen xv human fetal pancreas incontinentia pigmenti cf patients cftr transcripts tumor suppression cftr promoter androgen receptor sperm maturation cancer research human molecular genetics epigenetics carcinogenesis

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Promoter-Dependent Upstream Activator Augments Cftr Expression in Diverse Epithelial Cell Types. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms (2024)

Giuliana C. CoattiNirbhayaditya VaghelaPulak GillurkarShih-Hsing LeirAnn Harris

geneticsgenetic engineeringmembrane biologymolecular cell biologygene expressiongene functiontranscription regulationgene regulationgene regulatory networksmolecular physiologycell regulationgenome biologyimmunologybiotechnologycell biologymolecular and cellular biologymammalian biologycellular biochemistry

Investigating Adverse Genomic and Regulatory Changes Caused by Replacement of the Full-Length Cftr Cdna Using Cas9 and Aav. Molecular Therapy — Nucleic Acids (2024)

Sriram VaidyanathanJenny L KerschnerAlekh ParanjapyeVrishti SinhaBrian LinTracy A BedrosianAdrian J ThrasherGiandomenico TurchianoAnn HarrisMatthew H Porteus

geneticsgenetic engineeringregulatory changesgene expressiongene therapydna repairrna biologyadverse genomicnucleic acidsgenome biologyfull-length cftr cdnaimmunologynucleic acid amplificationgenome editinggene editingbiological engineering

Stellate Cells Are in Utero Markers of Pancreatic Disease in Cystic Fibrosis. Molecular Medicine (2024)

Shih-Hsing LeirSvyatoslav TkachenkoAlekh ParanjapyeFrederick MecklerArnaud J. Van WettereJenny L. KerschnerElizabeth KuznetsovMakayla SchachtPulak GillurkarMisha RegouskiIuri Viotti PerisseCheyenne M. MarriottYing LiuIan BundersonKenneth L. WhiteIrina A. PolejaevaAnn Harris

pathologygene expressioncftr −/− pancreastissue (biology)molecular physiologycystic fibrosismolecular gastroenterologydevelopmental biologypancreas transplantationstellate cellsfibrosistranscriptomecell biologymolecular diagnostics

The Impact of Genomic Distance on Enhancer‐Promoter Interactions at the Cftr Locus. Journal of Cellular and Molecular Medicine (2024)

Jenny L. KerschnerFrederick MecklerGiuliana C. CoattiNirbhayaditya VaghelaAlekh ParanjapyeAnn Harris

geneticspopulation geneticshuman geneticsmolecular geneticsgenomicsenhancer-promoter interactionsgenomic distancemolecular biologygenome biologycell biologymolecular and cellular biologycellular biology

194 Investigating the Role of Bromodomain-Containing 8 Isoforms in the Innate Immune Response of Human Airway Epithelial Cells. Journal of Cystic Fibrosis (2023)

J. BrowneE. BrusciaA. GarrisonA. HarrisM. Egan

innate immune responsecystic fibrosismolecular biologyimmunologycell biology

279 Cellular Heterogeneity in the 16Hbe14Oairway Epithelial Line Affects Functional Readouts. Journal of Cystic Fibrosis (2023)

J. KerschnerA. ParanjapyeA. Harris

functional readoutscellular heterogeneitycystic fibrosisimmunologycell biologyepithelial line

Cellular Heterogeneity in the 16Hbe14O − Airway Epithelial Line Impacts Biological Readouts. Physiological Reports (2023)

Jenny L. KerschnerAlekh ParanjapyeAnn Harris

health sciencesapplied physiologycellular heterogeneityphysiological researchcellular physiologycell biologyhuman physiologyelectrophysiologyphysiology

Functional Genomics of the Human Epididymis: Further Characterization of Efferent Ducts and Model Systems by Single‐Cell Rna Sequencing Analysis. Andrology (2023)

Shih‐Hsing LeirAlekh ParanjapyeAnn Harris

neurologyfunctional genomicsmodel systemsgenomicsandrologyefferent ductshuman epididymis

Transcriptomic Analysis of Lung Development in Wildtype and Cftr−/− Sheep Suggests an Early Inflammatory Signature in the Cf Distal Lung. Functional & Integrative Genomics (2023)

Jenny L. KerschnerAlekh ParanjapyeMakayla SchachtFrederick MecklerFelix HuangGurkan BebekArnaud J. Van WettereMisha RegouskiIuri Viotti PerisseKenneth L. WhiteIrina A. PolejaevaShih-Hsing LeirAnn Harris

geneticsfunctional genomicspulmonary diseasesgene expressionrespiratory medicineinflammationcellular differentiationcystic fibrosismolecular physiologydevelopmental biologyorgan developmentimmunologyinflammatory responsedevelopmental immunology

An Ectopic Enhancer Restores Cftr Expression Through De Novo Chromatin Looping. Gene Therapy (2022)

Jenny L. KerschnerAlekh ParanjapyeNirbhayaditya VaghelaMichael D. WilsonAnn Harris

geneticschromatin loopingmedicinegene therapymolecular biologychromatin

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Ann Harris

Professor

Case Western Reserve University

Affiliations

School of Medicine

Genetics and Genome Sciences

Ann Harris is currently serving as a Genetics And Genome Sciences Professor at Case Western Reserve University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Ann Harris

Case Western Reserve University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Promoter-Dependent Upstream Activator Augments Cftr Expression in Diverse Epithelial Cell Types. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms (2024)

Giuliana C. CoattiNirbhayaditya VaghelaPulak GillurkarShih-Hsing LeirAnn Harris

Investigating Adverse Genomic and Regulatory Changes Caused by Replacement of the Full-Length Cftr Cdna Using Cas9 and Aav. Molecular Therapy — Nucleic Acids (2024)

Sriram VaidyanathanJenny L KerschnerAlekh ParanjapyeVrishti SinhaBrian LinTracy A BedrosianAdrian J ThrasherGiandomenico TurchianoAnn HarrisMatthew H Porteus

Stellate Cells Are in Utero Markers of Pancreatic Disease in Cystic Fibrosis. Molecular Medicine (2024)

The Impact of Genomic Distance on Enhancer‐Promoter Interactions at the Cftr Locus. Journal of Cellular and Molecular Medicine (2024)

Jenny L. KerschnerFrederick MecklerGiuliana C. CoattiNirbhayaditya VaghelaAlekh ParanjapyeAnn Harris

194 Investigating the Role of Bromodomain-Containing 8 Isoforms in the Innate Immune Response of Human Airway Epithelial Cells. Journal of Cystic Fibrosis (2023)

J. BrowneE. BrusciaA. GarrisonA. HarrisM. Egan

innate immune responsecystic fibrosismolecular biologyimmunologycell biology

279 Cellular Heterogeneity in the 16Hbe14Oairway Epithelial Line Affects Functional Readouts. Journal of Cystic Fibrosis (2023)

J. KerschnerA. ParanjapyeA. Harris

functional readoutscellular heterogeneitycystic fibrosisimmunologycell biologyepithelial line

Cellular Heterogeneity in the 16Hbe14O − Airway Epithelial Line Impacts Biological Readouts. Physiological Reports (2023)

Jenny L. KerschnerAlekh ParanjapyeAnn Harris

health sciencesapplied physiologycellular heterogeneityphysiological researchcellular physiologycell biologyhuman physiologyelectrophysiologyphysiology

Functional Genomics of the Human Epididymis: Further Characterization of Efferent Ducts and Model Systems by Single‐Cell Rna Sequencing Analysis. Andrology (2023)

Shih‐Hsing LeirAlekh ParanjapyeAnn Harris

neurologyfunctional genomicsmodel systemsgenomicsandrologyefferent ductshuman epididymis

Transcriptomic Analysis of Lung Development in Wildtype and Cftr−/− Sheep Suggests an Early Inflammatory Signature in the Cf Distal Lung. Functional & Integrative Genomics (2023)

An Ectopic Enhancer Restores Cftr Expression Through De Novo Chromatin Looping. Gene Therapy (2022)

Jenny L. KerschnerAlekh ParanjapyeNirbhayaditya VaghelaMichael D. WilsonAnn Harris

geneticschromatin loopingmedicinegene therapymolecular biologychromatin

1
2
3
4
5
19
10 / page

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genetics

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Harvard University

critical care

cardiovascular disease

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animal genetics

cancer research