Faculty

Institution

Unit

Venue

Ali Khoshnan

PhD

University of Southern California

Affiliations

Keck School of Medicine

Physiology and Neuroscience

Ali Khoshnan is currently serving as a Keck School Of Medicine PhD at University of Southern California.

Honors

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Experiences

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Education

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Ali Khoshnan

University of Southern California

PhD

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neuroscience immunology neurology huntington's disease virology signal transduction cell signaling genetics immune responses cell death gene expression protein science molecular neurodegeneration virus research molecular virology viral genetics signaling pathways cell regulation molecular neuroscience human genetics medicinal research mammalian biology molecular physiology molecular cell biology molecular neurobiology microbial virus clinical immunology cellular immune responses molecular immunology antibody engineering molecular regulation apoptosis cellular biochemistry general virology cytokines brain science viral evolution virus-host interactions medical genetics degenerative pathology immunochemistry nf-kb cascade ikb kinase complex trichomonas vaginalis virus bcl-xl expression huntingtin neurotoxicity aging cell medical virology biochemical sciences enzyme inhibition clinical microbiology nanoparticle research viral hepatitis viral structural protein viral oncology adaptive immune system neuroprotection protein function host specificity protein expression mechanisms of action biomolecular interactions viral pathogenesis rna biology virus transmission ikk activation polyglutamine repeat inflammatory kinase ikk core protein tumor necrosis factor cytoplasmic domain anti-apoptotic effects intracellular expression mutant huntingtin aggregation anti-huntingtin antibodies protein kinase cth molecular genetics degenerative disease insect molecular biology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Gut Microbiota as a Modifier of Huntington’s Disease Pathogenesis. Journal of Huntington s Disease (2024)

huntington's diseasemolecular neurodegenerationpathogenesisdysbiosisdigestive diseasesmicrobiologygut microbesgut microbiotamicrobiomegenetics

CORRIGENDUM: Gut Bacteria Regulate the Pathogenesis of Huntington's Disease in Drosophila Model. Frontiers in Neuroscience (2022)

Anjalika ChongthamJung Hyun YooTheodore M. ChinNgozi D. AkingbesoteAinul HudaJ. Lawrence MarshAli Khoshnan

huntington's diseaseneurologyanimal scienceinsect molecular biologyneuroanatomypathogenesisgut bacterianeuroscienceavian biologyinsect sciencemammalian biologydrosophila modelsystems biologyentomologymicrobial pathogenesis

Ikkβ Signaling Mediates Metabolic Changes in the Hypothalamus of a Huntington Disease Mouse Model. iScience (2022)

Rana Soylu-KucharzAli KhoshnanÅsa Petersén

huntington's diseaseneurologyendocrinologyanimal physiologysystems neurosciencephysiologyneuroanatomymetabolic regulationmedicinal researchcellular physiologyneurosciencemolecular neurobiologysignaling pathwaysmolecular physiologymitochondrial functionsignal transductionmammalian biologymammalian physiology

Amplification of Neurotoxic Httex1 Assemblies in Human Neurons. Neurobiology of Disease (2021)

Anjalika ChongthamJ. Mario IsasNitin K. PandeyAnoop RawatJung Hyun YooTara MastroMary B. KennedyRalf LangenAli Khoshnan

neurologyneuronshuman neuronsneuroscience

Gut Bacteria Regulate the Pathogenesis of Huntington’s Disease in Drosophila Model. bioRxiv (Cold Spring Harbor Laboratory) (2021)

Anjalika ChongthamJung Hyun YooTheodore M. ChinNgozi D. AkingbesoteAinul HudaAli Khoshnan

huntington's diseaseinsect molecular biologypathogenesisgut bacteriadevelopmental biologymicrobial pathogenesis

Small, Seeding-Competent Huntingtin Fibrils Are Prominent Aggregate Species in Brains of Zq175 Huntington’s Disease Knock-in Mice. Frontiers in Neuroscience (2021)

Franziska SchindlerNicole PraedelNancy NeuendorfSeverine KunzSigrid SchnoeglMichael A. MasonBridget A. TaxyGillian P. BatesAli KhoshnanJosef PrillerJan GrimmMarcel MaierAnnett BoeddrichErich E. Wanker

huntington's diseaseneurologyneuroanatomyneurosciencebrain scienceseeding-competent huntingtin fibrils

Sonicated Fibrils of Huntingtin Exon-1 Preferentially Seed Neurons and Produce Toxic Assemblies. bioRxiv (Cold Spring Harbor Laboratory) (2021)

Anjalika ChongthamJ Mario IsasNitin K PandeyAnoop RawatJung Hyun YooTara MastroMarry KennedyRalf LangenAli Khoshnan

neurologyneurosciencedevelopmental biologyfibrinolysisdevelopmental neurobiologytoxic assemblies

Identification of Distinct Conformations Associated With Monomers and Fibril Assemblies of Mutant Huntingtin. Human Molecular Genetics (2018)

Jan KoJ Mario IsasAdam SabbaughJung Hyun YooNitin K PandeyAnjalika ChongthamMark LadinskyWei-Li WuHeike RohwederAndreas WeissDouglas MacdonaldIgnacio Munoz-SanjuanRalf LangenPaul H PattersonAli Khoshnan

mutagenesismutant huntingtinconformational studiesprotein scienceprotein chemistryfibril assembliesbiochemistrymolecular geneticsdistinct conformationsmolecular biologyprotein structurehuman geneticsprotein assemblystructural biologygenetics

Ikkβ and Mutant Huntingtin Interactions Regulate the Expression of Il-34: Implications for Microglial-Mediated Neurodegeneration in Hd. Human Molecular Genetics (2017)

Ali KhoshnanAdam SabbaughBarbara CalaminiSteven A MarineroDenise E DunnJung Hyun YooJan KoDonald C LoPaul H Patterson

neurogeneticsmolecular neurodegenerationmicroglial-mediated neurodegenerationprotein sciencecellular neurobiologymolecular neurobiologyneurosciencefunctional regulationmolecular geneticsmolecular biologybrain-immune interactionmolecular neurosciencehuman geneticssignal transductionmedical geneticsmutant huntingtin interactionsgenetics

Antibodies and Intrabodies Against Huntingtin: Production and Screening of Monoclonals and Single-Chain Recombinant Forms. Methods in molecular biology (2013)

Ali KhoshnanSusan OuJan KoPaul H. Patterson

single-chain recombinant formsimmunologynanotechnologyantibody engineeringpharmacologymolecular biologyantibody screening

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Ali Khoshnan

PhD

University of Southern California

Affiliations

Keck School of Medicine

Physiology and Neuroscience

Ali Khoshnan is currently serving as a Keck School Of Medicine PhD at University of Southern California.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Ali Khoshnan

University of Southern California

PhD

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Gut Microbiota as a Modifier of Huntington’s Disease Pathogenesis. Journal of Huntington s Disease (2024)

huntington's diseasemolecular neurodegenerationpathogenesisdysbiosisdigestive diseasesmicrobiologygut microbesgut microbiotamicrobiomegenetics

CORRIGENDUM: Gut Bacteria Regulate the Pathogenesis of Huntington's Disease in Drosophila Model. Frontiers in Neuroscience (2022)

Anjalika ChongthamJung Hyun YooTheodore M. ChinNgozi D. AkingbesoteAinul HudaJ. Lawrence MarshAli Khoshnan

Ikkβ Signaling Mediates Metabolic Changes in the Hypothalamus of a Huntington Disease Mouse Model. iScience (2022)

Rana Soylu-KucharzAli KhoshnanÅsa Petersén

Amplification of Neurotoxic Httex1 Assemblies in Human Neurons. Neurobiology of Disease (2021)

Anjalika ChongthamJ. Mario IsasNitin K. PandeyAnoop RawatJung Hyun YooTara MastroMary B. KennedyRalf LangenAli Khoshnan

neurologyneuronshuman neuronsneuroscience

Gut Bacteria Regulate the Pathogenesis of Huntington’s Disease in Drosophila Model. bioRxiv (Cold Spring Harbor Laboratory) (2021)

Anjalika ChongthamJung Hyun YooTheodore M. ChinNgozi D. AkingbesoteAinul HudaAli Khoshnan

huntington's diseaseinsect molecular biologypathogenesisgut bacteriadevelopmental biologymicrobial pathogenesis

Small, Seeding-Competent Huntingtin Fibrils Are Prominent Aggregate Species in Brains of Zq175 Huntington’s Disease Knock-in Mice. Frontiers in Neuroscience (2021)

huntington's diseaseneurologyneuroanatomyneurosciencebrain scienceseeding-competent huntingtin fibrils

Sonicated Fibrils of Huntingtin Exon-1 Preferentially Seed Neurons and Produce Toxic Assemblies. bioRxiv (Cold Spring Harbor Laboratory) (2021)

Anjalika ChongthamJ Mario IsasNitin K PandeyAnoop RawatJung Hyun YooTara MastroMarry KennedyRalf LangenAli Khoshnan

neurologyneurosciencedevelopmental biologyfibrinolysisdevelopmental neurobiologytoxic assemblies

Identification of Distinct Conformations Associated With Monomers and Fibril Assemblies of Mutant Huntingtin. Human Molecular Genetics (2018)

Ikkβ and Mutant Huntingtin Interactions Regulate the Expression of Il-34: Implications for Microglial-Mediated Neurodegeneration in Hd. Human Molecular Genetics (2017)

Ali KhoshnanAdam SabbaughBarbara CalaminiSteven A MarineroDenise E DunnJung Hyun YooJan KoDonald C LoPaul H Patterson

Antibodies and Intrabodies Against Huntingtin: Production and Screening of Monoclonals and Single-Chain Recombinant Forms. Methods in molecular biology (2013)

Ali KhoshnanSusan OuJan KoPaul H. Patterson

single-chain recombinant formsimmunologynanotechnologyantibody engineeringpharmacologymolecular biologyantibody screening

1
2
3
4
10 / page

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Similar Faculty Members

J. Marie Hardwick

Institution

Johns Hopkins University

cell death

molecular biology

Edward S. Mocarski

Institution

Stanford University

immunology

infectious diseases

Ganes C. Sen

Institution

Case Western Reserve University

viral oncology

viral pathogenesis

Bellur S Prabhakar

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University of Illinois Chicago

cellular therapy

immune response

Glen N. Barber, Ph.D

Institution

University of Miami

microbial infection

immunology

Jack A Elias

Institution

Brown University

respiratory medicine

cytokine

Timothy Scott Blackwell, M.D.

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Vanderbilt University

respiratory medicine

immunology

James R. Goldenring

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Vanderbilt University

gastrointestinal oncology

gastroenterology

Kamel Khalili

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Temple University

neuroscience

neurodegenerative disease

Jenny Ting

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University of North Carolina at Chapel Hill

gene discovery

innate immune system