Faculty

Institution

Unit

Venue

W. K. Alfred Yung

The University of Texas MD Anderson Cancer Center

Affiliations

Center Of Brain Tumour

Department Of Breast Surgical Oncology

Division Of Cancer Medicine

Department Of Thoracic-Head And Neck Medical Oncology

Division Of Cancer Medicine

The University of Texas MD Anderson Cancer Center

NoneW. K. Alfred Yung is currently serving as a Center Of Brain Tumour faculty at The University of Texas Md Anderson Cancer Center.

Honors

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Experiences

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Education

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W. K. Alfred Yung

The University of Texas MD Anderson Cancer Center

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brain tumor research neuro-oncology gliomas oncology neurology tumor biology cancer treatment cancer research radiation oncology oncogenes cell biology cancer biology medicinal research cancer cells molecular biology molecular cancer vascular biology therapeutic targets anti-cancer agents tumor targeting cancer care cancer genetics tumor suppressors cancer genomics pharmacotherapy enzyme inhibition clinical trials cancer growth gene expression radiation therapy cancer discovery surgical oncology cellular therapy neurosurgery tumor innervation neuroradiology tumor heterogeneity cell death cancer management novel therapies cell regulation clinical neurology phase ii study phase ii trial molecular cell biology signaling pathways recurrent glioblastoma viral oncology therapeutic efficacy clinical radiation oncology angiogenesis apoptosis recurrent malignant gliomas tumoral pathology brain lesion receptor tyrosine kinases metronomic therapy recurrent malignant glioma human glioma cells prognosis glioblastoma multiforme prognostic evaluation oncologic imaging neurotology malignant disease human gliomas malignant gliomas cell proliferation cell growth glioma cells recurrent glioblastoma multiforme health-related quality human glioblastoma malignant glioma brain tumors prognostic significance

Notable Scholarly Works

Notable Federal Grants

Collaborators

Improved Overall Survival in an Anti-Pd-L1 Treated Cohort of Newly Diagnosed Glioblastoma Patients is Associated With Distinct Immune, Mutation, and Gut Microbiome Features: A Single Arm Prospective Phase I/II Trial. Nature Communications (2025)

cancer immunotherapyoverall survivalmedicineoncologyneuro-oncologybrain tumor researchcancer discoverygut-organ axisdistinct immunemicrobiome featuresgut microbesimmunotherapyimmunologygliomasimmune checkpoint inhibitorsprognostic biomarkersmolecular diagnostics

Oncogenic Drivers Shape the Tumor Microenvironment in Human Gliomas. bioRxiv (Cold Spring Harbor Laboratory) (2025)

pathologyoncogenestumor microenvironmenttumor heterogeneityneuro-oncologybrain tumor researchbiological microenvironmentstumor biologygliomasoncogenic driverscell biologycancer growth

Os05.2.a Deciphering the Longitudinal Trajectories of Glioblastoma Ecosystems by Integrative Single-Cell Genomics. Neuro-Oncology (2025)

single-cell analysiscancer cellstumor heterogeneityneuro-oncologybrain tumor researchcancer genomicssingle cell sequencingsystems biologytumor biologygliomascell biologyspatial omics

Stem-04. Longitudinal Dna Methylation Change Fuels Disease Progression Through Altered Cell State Differentiation in Idh-Mutant Glioma. Neuro-Oncology (2025)

geneticscancer cellsbrain tumor researchcancer genomicstumor biologygliomasepigeneticscell biologyepigenetic changesepigenomics

The Multilayered Transcriptional Architecture of Glioblastoma Ecosystems. Nature Genetics (2025)

Masashi NomuraAvishay SpitzerKevin C JohnsonLuciano GarofanoDjamel Nehar-BelaidNoam Galili DarnellAlissa C GreenwaldLillian BussemaYoung Taek OhFrederick S VarnFulvio D'AngeloSimon GritschKevin J AndersonSimona MigliozziL Nicolas Gonzalez CastroTamrin ChowdhFuryNicolas RobineCatherine ReevesJong Bae ParkAnuja LipsaFrank HertelAnna GolebiewskaSimone P NiclouLabeeba NusratSorcha KelletSunit DasHyo Eun MoonSun Ha PaekFranck BielleAlice LaurengeAnna Luisa Di StefanoBertrand MathonAlberto PiccaMarc SansonShota TanakaNobuhito SaitoDavid M AshleyStephen T KeirKeith L LigonJason T HuseW K Alfred YungAnna LasorellaRoel G W VerhaakAntonio IavaroneMario L SuvàItay Tirosh

small rnapathologygene functionrna biologymembrane biologybiomolecular engineeringcarcinogenesisvascular biologymultilayered transcriptional architecturemolecular cell biologygene expressionstructural biologytranscriptomics technologyimmunologystem cell researchoncogenesglioblastoma ecosystemscancer discoverytranscription regulationtherapeutic targets

Tumor-Initiating Genetics and Therapy Drive Divergent Molecular Evolution in Idh-Mutant Gliomas. bioRxiv (Cold Spring Harbor Laboratory) (2025)

geneticsmolecular canceroncogenestumor heterogeneitybrain tumor researchradiation oncologyidh-mutant gliomassystems biologycancer geneticsgliomascarcinogenesistumor-initiating genetics

Epco-26. Longitudinal Single-Cell Analyses Identify Drivers of Genetic, Epigenomic, and Cellular Evolution in Idh-Mutant Glioma. Neuro-Oncology (2024)

Kevin JohnsonAvishay SpitzerFrederick VarnMasashi NomuraLuciano GarofanoTamrin ChowdhuryKevin AndersonFulvio D’AngeloLillian BussemaSimon GritschYoung Taek OhHyo-Eun MoonSun Ha PaekFranck BielleAlice LaurengeAnna-Luisa Di StefanoBertrand MathonAlberto PiccaMarc SansonAnuja LipsaFrank HertelZheng ZhaoQianghu WangTao JiangBeth HermesNader SanaiAnna GolebiewskaSimone NiclouJason HuseW K Alfred YungAnna LasorellaMario SuvàAntonio IavaroneItay TiroshRoel Verhaak

geneticssingle-cell analysiscellular evolutionidh-mutant gliomaneuro-oncologylongitudinal single-cell analysesgliomasepigenetics

Epco-34. Deciphering the Longitudinal Trajectories of Glioblastoma by Integrative Single-Cell Genomics. Neuro-Oncology (2024)

Avishay SpitzerKevin C JohnsonMasashi NomuraLuciano GarofanoDjamel Nehar-belaidNoam Galili DarnellAlissa C GreenwaldLillian BussemaYoung Taek OhFrederick S VarnFulvio D’AngeloSimon GritschKevin J AndersonSimona MigliozziL Nicolas Gonzalez CastroTamrin ChowdhuryNicolas RobineCatherine ReevesJong Bae ParkAnuja LipsaFrank HertelAnna GolebiewskaSimone P NiclouLabeeba NusratSorcha KelletSunit DasHyo-Eun MoonSun Ha PaekFranck BielleAlice LaurengeAnna Luisa Di StefanoBertrand MathonAlberto PiccaMarc SansonShota TanakaNobuhito SaitoDavid M AshleyStephen T KeirJason T HuseW K Alfred YungAnna LasorellaAntonio IavaroneRoel G W VerhaakItay TiroshMario L Suvà

longitudinal trajectoriesneurosciencebrain tumor researchneuro-oncologycancer genomicsgliomasintegrative single-cell genomics

Ltbk-02. Evaluation of Paxalisib in Gbm Agile Phase 3 Registration Platform Trial for Newly Diagnosed and Recurrent Glioblastoma. Neuro-Oncology (2024)

Ingo K MellinghoffTimothy CloughesyBrian AlexanderDonald A BerryMeredith BuxtonWebster CaveneeHoward ColmanJohn de GrootBenjamin M EllingsonGary B GordonAndrew B LassmanMichael LimMustafa KhasrawJames PerryErik P SulmanMichael WellerPatrick WenW K Alfred YungNicholas BerryTodd GravesMichelle DetryE M Viktoria HyddmarkAdam JohnssonHeather KlingAnna McGlothlinAshley PowellSarah UntchElisa AquilantiNicholas BlondinBrian BoulmayMacarena de la FuenteJan DrappatzJustin JordanThomas J KaleyMina LobbousTom MikkelsenHerbert NewtonScott OwenKatherine PetersDavid SchiffWendy ShermanShiao-Pei WeathersMichael YoussefJohn FriendEudocia Lee

neurosurgerybrain lesionearly diagnosisneuroscienceneuro-oncologygliomasvascular biologymolecular diagnosticsneurologyfield trialoncologyregistration platform trialbrain tumor researchcancer managementclinical trialsurologyneuroimagingrecurrent glioblastomamedicinal researchclinical neurology

Ctim-20. Systemic Immune Correlates Associated With Long-Term Survival After Therapeutic Adenovirus (Dnx2401) Plus Interferon Gamma for Recurrent Glioblastoma Effect Trial (Target): A Randomized Phase 1 Trial. Neuro-Oncology (2023)

Chibawanye EneSanjay SinghLynette PhillipsRaja VenkataramanVinay PuduvalliDeep SinghNam TramJames LongMartin BradyRaghu RaghavanFrank TufaroBrett EwaldP J AnandJ Bradley ElderKaren FinkW K Alfred YungMarta Penas-PradoNick NavinBenjamin LarmanCandelaria Gomez-ManzanoJuan Fueyo-MargaretoJoanna PeterkinFrederick Lang

neurologycancer immunotherapytherapeutic adenovirusinterferon gammamedicineoncologyneuro-oncologybrain tumor researchsystemic immune correlateslong-term survivalviral oncologytumor biologyimmunologygliomas

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W. K. Alfred Yung

The University of Texas MD Anderson Cancer Center

Affiliations

Center Of Brain Tumour

Department Of Breast Surgical Oncology

Division Of Cancer Medicine

Department Of Thoracic-Head And Neck Medical Oncology

Division Of Cancer Medicine

The University of Texas MD Anderson Cancer Center

NoneW. K. Alfred Yung is currently serving as a Center Of Brain Tumour faculty at The University of Texas Md Anderson Cancer Center.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

W. K. Alfred Yung

The University of Texas MD Anderson Cancer Center

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Oncogenic Drivers Shape the Tumor Microenvironment in Human Gliomas. bioRxiv (Cold Spring Harbor Laboratory) (2025)

pathologyoncogenestumor microenvironmenttumor heterogeneityneuro-oncologybrain tumor researchbiological microenvironmentstumor biologygliomasoncogenic driverscell biologycancer growth

Os05.2.a Deciphering the Longitudinal Trajectories of Glioblastoma Ecosystems by Integrative Single-Cell Genomics. Neuro-Oncology (2025)

single-cell analysiscancer cellstumor heterogeneityneuro-oncologybrain tumor researchcancer genomicssingle cell sequencingsystems biologytumor biologygliomascell biologyspatial omics

Stem-04. Longitudinal Dna Methylation Change Fuels Disease Progression Through Altered Cell State Differentiation in Idh-Mutant Glioma. Neuro-Oncology (2025)

geneticscancer cellsbrain tumor researchcancer genomicstumor biologygliomasepigeneticscell biologyepigenetic changesepigenomics

The Multilayered Transcriptional Architecture of Glioblastoma Ecosystems. Nature Genetics (2025)

Tumor-Initiating Genetics and Therapy Drive Divergent Molecular Evolution in Idh-Mutant Gliomas. bioRxiv (Cold Spring Harbor Laboratory) (2025)

geneticsmolecular canceroncogenestumor heterogeneitybrain tumor researchradiation oncologyidh-mutant gliomassystems biologycancer geneticsgliomascarcinogenesistumor-initiating genetics

Epco-26. Longitudinal Single-Cell Analyses Identify Drivers of Genetic, Epigenomic, and Cellular Evolution in Idh-Mutant Glioma. Neuro-Oncology (2024)

geneticssingle-cell analysiscellular evolutionidh-mutant gliomaneuro-oncologylongitudinal single-cell analysesgliomasepigenetics

Epco-34. Deciphering the Longitudinal Trajectories of Glioblastoma by Integrative Single-Cell Genomics. Neuro-Oncology (2024)

longitudinal trajectoriesneurosciencebrain tumor researchneuro-oncologycancer genomicsgliomasintegrative single-cell genomics

Ltbk-02. Evaluation of Paxalisib in Gbm Agile Phase 3 Registration Platform Trial for Newly Diagnosed and Recurrent Glioblastoma. Neuro-Oncology (2024)

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5
41
10 / page