Faculty

Institution

Unit

Venue

Alexandra E. Purdy

Amherst College

Affiliations

Department Of Biology

NoneAlexandra E. Purdy is currently serving as a Biology faculty at Amherst College.

Honors

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Experiences

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Education

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Alexandra E. Purdy

Amherst College

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microbiology infectious diseases microbial pathogenesis pathogens bacteria pathogenesis pathogenic bacteria molecular biology virology applied microbiology environmental microbiology clinical microbiology bacteriology molecular microbiology virulence factors biochemistry membrane biology microbial ecology avian biology pathogen characterization microbial physiology disease gene identification cholix toxin vibrio cholerae acetate switch biological chemistry medicinal research liver physiology cell metabolism gut microbes digestive diseases cellular physiology biological invasions geophysical research insect biochemistry genome biology stem cell research metabolic regulation insulin signaling host-microbe interactions signaling pathways mutagenesis host factors developmental genetics pathway analysis microbial diversity toxinology microbial genetics microbial disease natural gas hydrates gas hydrates natural gas hydrate system global healthcare covid-19 pandemic global health crisis cross-sectional studies novel adp-ribosylating factor lipid metabolism intestinal pathogen disrupts selective colonization arthropod intestine vibrio cholerae quorum arthropod host genome content environmental strains hydrate ridge biogeochemical investigations marine methane seeps imd pathway

Notable Scholarly Works

Notable Federal Grants

Collaborators

Economic Crisis and Post-Covid Adaptations in Directly Observed Therapy Practices Among Tuberculosis Patients in Colombo, Sri Lanka: A Cross-Sectional Study. medRxiv (2025)

public healtheconomic crisisepidemiologyglobal health crisistuberculosiscross-sectional studiescovid-19 pandemicglobal healthinfectious diseases (medical specialty)communicable diseasesinternational healthcovid-19population healthpublic health preparednessglobal healthcaresri lanka

A Putative Acetylation System in Vibrio Cholerae Modulates Virulence in Arthropod Hosts. Applied and Environmental Microbiology (2018)

clinical microbiologyinfectious diseasesarthropod hostspathogenic bacteriainvertebrate pathologypathogenesisbiofilmsmolecular microbiologyputative acetylation systemmicrobiologybacteriapathogensvirulence factorsmolecular biologyapplied microbiologymicrobial pathogenesis

Fly Models of Vibrio Cholerae Infection and Colonization. Methods in molecular biology (2018)

clinical microbiologyinfectious diseasespathogenic bacteriapathogenesismicrobiologypathogenscommunicable diseasesfly modelspathogen characterizationmicrobial pathogenesis

Modulation of Crbs-Dependent Activation of the Acetate Switch in Vibrio Cholerae. Journal of Bacteriology (2018)

clinical microbiologyinfectious diseasespathogenic bacteriapathogenesismicroorganismsmolecular microbiologymicrobial physiologyacetate switchbiochemistrymicrobiologyvirulence factorscrbs-dependent activationvibrio choleraebacteriologyapplied microbiologymicrobial pathogenesis

Activation of Vibrio Cholerae Quorum Sensing Promotes Survival of an Arthropod Host. Nature Microbiology (2017)

Layla KamareddineAdam C. N. WongAudrey S. VanhoveSaiyu HangAlexandra E. PurdyKatharine Kierek-PearsonJohn M. AsaraAfsar AliJ. Glenn Morris JrPaula I. Watnick

infectious diseasesvirologyimmunologyarthropod hostmicrobiologyavian biologyvibrio cholerae quorummicrobial ecology

Regulation of Acetyl-Coa Synthetase Transcription by the Crbs/R Two-Component System is Conserved in Genetically Diverse Environmental Pathogens. PLoS ONE (2017)

crbs/r two-component systemacetyl-coa synthetase transcriptionmolecular plant pathologymolecular metabolismpathogenesismolecular microbiologydiverse environmental pathogensmicrobiologypathogensvirulence factorstranscription (biology)molecular biologyfungal geneticsmicrobial geneticsbacteriologygene expressionmicrobial pathogenesis

The Acetate Switch of an Intestinal Pathogen Disrupts Host Insulin Signaling and Lipid Metabolism. Cell Host & Microbe (2014)

Saiyu HangAlexandra E. PurdyWilliam P. RobinsZhipeng WangManabendra MandalSarah ChangJohn J. MekalanosPaula I. Watnick

pathologyintestinal pathogen disruptsliver physiologymicrobiomehost-microbe interactionsgastroenterologycell signalingmicrobial physiologycell biologyacetate switchgut microbesinsulin signalinglipid metabolismcellular physiologydigestive diseasescell metabolismmicrobiologysignaling pathwaysmetabolic regulationmembrane biologysignal transduction

Mutations in the Imd Pathway and Mustard Counter Vibrio Cholerae Suppression of Intestinal Stem Cell Division in Drosophila. mBio (2013)

Zhipeng WangSaiyu HangAlexandra E. PurdyPaula I. Watnick

molecular and cellular biologyinsect molecular biologyinsect biochemistrymutagenesis (molecular biology technique)stem cell researchmutagenesisimd pathwayimmunologygenome biologydevelopmental biologydisease gene identificationmembrane biologypathway analysisdevelopmental geneticsgene expressionhost factorsgeneticsmicrobial pathogenesis

Spatially Selective Colonization of the Arthropod Intestine Through Activation of Vibrio Cholerae Biofilm Formation. Proceedings of the National Academy of Sciences (2011)

Alexandra E. PurdyPaula I. Watnick

epidemiologyapplied microbiologyinfectious diseasesvirologybiofilmsarthropod intestinemicrobiologyavian biologybiological invasionsselective colonizationenvironmental microbiologymicrobial ecology

Diversity and Distribution of Cholix Toxin, a Novel Adp‐Ribosylating Factor From Vibrio Cholerae. Environmental Microbiology Reports (2010)

Alexandra E. PurdyDeborah BalchMarcial Leonardo Lizárraga‐PartidaMohammad Sirajul IslamJaime Martinez‐UrtazaAnwar HuqRita R. ColwellDouglas H. Bartlett

infectious diseasesvirologytoxinologymicrobiologybacteriacholix toxinmicrobial diversityenvironmental microbiology

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Alexandra E. Purdy

Amherst College

Affiliations

Department Of Biology

NoneAlexandra E. Purdy is currently serving as a Biology faculty at Amherst College.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Alexandra E. Purdy

Amherst College

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Economic Crisis and Post-Covid Adaptations in Directly Observed Therapy Practices Among Tuberculosis Patients in Colombo, Sri Lanka: A Cross-Sectional Study. medRxiv (2025)

A Putative Acetylation System in Vibrio Cholerae Modulates Virulence in Arthropod Hosts. Applied and Environmental Microbiology (2018)

Fly Models of Vibrio Cholerae Infection and Colonization. Methods in molecular biology (2018)

clinical microbiologyinfectious diseasespathogenic bacteriapathogenesismicrobiologypathogenscommunicable diseasesfly modelspathogen characterizationmicrobial pathogenesis

Modulation of Crbs-Dependent Activation of the Acetate Switch in Vibrio Cholerae. Journal of Bacteriology (2018)

Activation of Vibrio Cholerae Quorum Sensing Promotes Survival of an Arthropod Host. Nature Microbiology (2017)

Layla KamareddineAdam C. N. WongAudrey S. VanhoveSaiyu HangAlexandra E. PurdyKatharine Kierek-PearsonJohn M. AsaraAfsar AliJ. Glenn Morris JrPaula I. Watnick

infectious diseasesvirologyimmunologyarthropod hostmicrobiologyavian biologyvibrio cholerae quorummicrobial ecology

Regulation of Acetyl-Coa Synthetase Transcription by the Crbs/R Two-Component System is Conserved in Genetically Diverse Environmental Pathogens. PLoS ONE (2017)

The Acetate Switch of an Intestinal Pathogen Disrupts Host Insulin Signaling and Lipid Metabolism. Cell Host & Microbe (2014)

Saiyu HangAlexandra E. PurdyWilliam P. RobinsZhipeng WangManabendra MandalSarah ChangJohn J. MekalanosPaula I. Watnick

Mutations in the Imd Pathway and Mustard Counter Vibrio Cholerae Suppression of Intestinal Stem Cell Division in Drosophila. mBio (2013)

Zhipeng WangSaiyu HangAlexandra E. PurdyPaula I. Watnick

Spatially Selective Colonization of the Arthropod Intestine Through Activation of Vibrio Cholerae Biofilm Formation. Proceedings of the National Academy of Sciences (2011)

Alexandra E. PurdyPaula I. Watnick

epidemiologyapplied microbiologyinfectious diseasesvirologybiofilmsarthropod intestinemicrobiologyavian biologybiological invasionsselective colonizationenvironmental microbiologymicrobial ecology

Diversity and Distribution of Cholix Toxin, a Novel Adp‐Ribosylating Factor From Vibrio Cholerae. Environmental Microbiology Reports (2010)

Alexandra E. PurdyDeborah BalchMarcial Leonardo Lizárraga‐PartidaMohammad Sirajul IslamJaime Martinez‐UrtazaAnwar HuqRita R. ColwellDouglas H. Bartlett

infectious diseasesvirologytoxinologymicrobiologybacteriacholix toxinmicrobial diversityenvironmental microbiology

1
2
10 / page