Faculty

Institution

Unit

Venue

Alex Brian Speers, N.D., M.C.R.

Assistant Professor of Neurology

Oregon Health & Science University

Affiliations

OHSU School of Medicine

Botanical Dietary Supplements Research Center (Benfra)

Department Of Pediatrics

Division Of Neurology

Oregon Health & Science University

Alex Brian Speers, N.d., M.c.r. is currently serving as a Botanical Dietary Supplements Research Center (Benfra) Assistant Professor of Neurology at Oregon Health & Science University.

Honors

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Experiences

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Education

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Alex Brian Speers, N.D., M.C.R.

Oregon Health & Science University

Assistant Professor of Neurology

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pharmacology neurology neuroscience alzheimer's disease medicine molecular neurodegeneration drug metabolism neuropharmacology clinical pharmacology neuroinflammation anxiety disorders psychopathology depression stress (biology) cognitive impairment biological psychiatry translational psychiatry psychological medicine mammalian biology molecular physiology pharmacological research medicinal research drug analysis applied pharmacology neuroscience of aging molecular metabolism cell metabolism phytotherapy research antioxidants functional foods stress biomarkers pathway analysis molecular neurobiology disease pathophysiology mitochondrial function pharmacokinetics aging-associated diseases neurochemical biomarkers protein misfolding nutraceutical ingredient herbal medicine herb-drug interactions withania somnifera ss-amyloid accumulation mouse model pharmacokinetic studies active centella asiatica centella asiatica digital evaluations baseline results digital biomarkers internal medicine translational research neuropathology geriatric psychiatry family medicine child neurology pediatrics medical sociology primary care health sciences neurodegenerative diseases individualized medicine nurse education medical history nursing chinese medicine dementia complementary medicine medical education integrative medicine health care alternative medicine nursing science

Notable Scholarly Works

Notable Federal Grants

Collaborators

Detect‐Ad (Digital Evaluations and Technologies Enabling Clinical Translation for Alzheimer’s Disease): Baseline Results of a Simulated Anti‐Amyloid Clinical Trial Using Digital Biomarkers. Alzheimer s & Dementia (2025)

neurologybiomarkersaging-associated diseasesdigital evaluationsbaseline resultsneurochemical biomarkersmolecular neurodegenerationneuroscience of agingalzheimer's diseaseneuroscienceneurodegenerative diseasesdigital biomarkers

Mode of Administration Influences Plasma Levels of Active Centella Asiatica Compounds in 5Xfad Mice While Markers of Neuroinflammation Remain Unaltered. Frontiers in Neuroscience (2024)

Alex B. SpeersKirsten M. WrightMikah S. BrandesNareg KedjejianDonald G. MatthewsMaya CarusoChristopher J. HarrisSeiji KoikeThuan NguyenJoseph F. QuinnAmala SoumyanathNora E. Gray

neuroinflammationpharmacologyneuropharmacologyactive centella asiaticainfectious diseasesneuroscience

Quantifying Withanolides in Plasma: Pharmacokinetic Studies and Analytical Methods. Nutrients (2024)

medicinepharmacologypharmacokinetic studiespharmacokineticsdrug metabolismdrug analysisapplied pharmacologyclinical pharmacology

Toward Optimized Clinical Trials of Botanical Dietary Supplements in Older Adults. Innovation in Aging (2024)

phytotherapy researchmedicineageingpharmacologynutraceutical ingredientantioxidantsfunctional foodsalternative medicineherbal medicinebioactive compoundsclinical trialsgeriatricsherb-drug interactionscomplementary medicinenutritionhealth sciences

Cqa_Plasma Data_Raw_10.17.23. Figshare (2023)

Investigating the Effects of Centella Asiatica on Neuroinflammation in Beta‐Amyloid Overexpressing Mice. Alzheimer s & Dementia (2023)

Alex B SpeersMikah S BrandesNareg E KedjejianDonald G MatthewsMaya CarusoKirsten M WrightJoseph F QuinnAmala SoumyanathNora E Gray

neurologyneuroinflammationalzheimer's diseasecentella asiaticaneuroscience

Pharmacokinetics and Pharmacodynamics of Key Components of a Standardized Centella Asiatica Product in Cognitively Impaired Older Adults: A Phase 1, Double-Blind, Randomized Clinical Trial. Antioxidants (2022)

Kirsten M. WrightMelissa BollenJason DavidAlex B. SpeersMikah S. BrandesNora E. GrayArmando Alcázar MagañaChristine McClureJan F. StevensClaudia S. MaierJoseph F. QuinnAmala Soumyanath

neurologycognitive impairmentpharmacology

Alters Metabolic Pathways Associated With Alzheimer's Disease in the 5Xfad Mouse Model of β-Amyloid Accumulation. Front Pharmacol (2021)

metabolic pathwayspharmacologyprotein misfoldingmolecular metabolismmolecular neurodegenerationalzheimer's diseaseneuroscienceneurodegenerative diseasesbiochemistrycell metabolism

Centella Asiatica Alters Metabolic Pathways Associated With Alzheimer’s Disease in the 5Xfad Mouse Model of ß-Amyloid Accumulation. Frontiers in Pharmacology (2021)

Alex B. SpeersManuel García-JaramilloAlicia FerynDonald G. MatthewsTalia LichtenbergMaya CarusoKirsten M. WrightJoseph F. QuinnJan F. StevensClaudia S. MaierAmala SoumyanathNora E. Gray

drug metabolismclinical pharmacologypathway analysismolecular neurobiologyneurologymedicineneuropharmacologyss-amyloid accumulationdisease pathophysiologymembrane biologyneurodegenerative diseasesmammalian biologymolecular neurodegenerationmolecular physiologypharmacological researchmouse modelpharmacologymitochondrial functionmedicinal researchalzheimer's disease

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Alex Brian Speers, N.D., M.C.R.

Assistant Professor of Neurology

Oregon Health & Science University

Affiliations

OHSU School of Medicine

Botanical Dietary Supplements Research Center (Benfra)

Department Of Pediatrics

Division Of Neurology

Oregon Health & Science University

Alex Brian Speers, N.d., M.c.r. is currently serving as a Botanical Dietary Supplements Research Center (Benfra) Assistant Professor of Neurology at Oregon Health & Science University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Alex Brian Speers, N.D., M.C.R.

Oregon Health & Science University

Assistant Professor of Neurology

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Mode of Administration Influences Plasma Levels of Active Centella Asiatica Compounds in 5Xfad Mice While Markers of Neuroinflammation Remain Unaltered. Frontiers in Neuroscience (2024)

Alex B. SpeersKirsten M. WrightMikah S. BrandesNareg KedjejianDonald G. MatthewsMaya CarusoChristopher J. HarrisSeiji KoikeThuan NguyenJoseph F. QuinnAmala SoumyanathNora E. Gray

neuroinflammationpharmacologyneuropharmacologyactive centella asiaticainfectious diseasesneuroscience

Quantifying Withanolides in Plasma: Pharmacokinetic Studies and Analytical Methods. Nutrients (2024)

medicinepharmacologypharmacokinetic studiespharmacokineticsdrug metabolismdrug analysisapplied pharmacologyclinical pharmacology

Toward Optimized Clinical Trials of Botanical Dietary Supplements in Older Adults. Innovation in Aging (2024)

Cqa_Plasma Data_Raw_10.17.23. Figshare (2023)

Investigating the Effects of Centella Asiatica on Neuroinflammation in Beta‐Amyloid Overexpressing Mice. Alzheimer s & Dementia (2023)

Alex B SpeersMikah S BrandesNareg E KedjejianDonald G MatthewsMaya CarusoKirsten M WrightJoseph F QuinnAmala SoumyanathNora E Gray

neurologyneuroinflammationalzheimer's diseasecentella asiaticaneuroscience

Kirsten M. WrightMelissa BollenJason DavidAlex B. SpeersMikah S. BrandesNora E. GrayArmando Alcázar MagañaChristine McClureJan F. StevensClaudia S. MaierJoseph F. QuinnAmala Soumyanath

neurologycognitive impairmentpharmacology

Alters Metabolic Pathways Associated With Alzheimer's Disease in the 5Xfad Mouse Model of β-Amyloid Accumulation. Front Pharmacol (2021)

metabolic pathwayspharmacologyprotein misfoldingmolecular metabolismmolecular neurodegenerationalzheimer's diseaseneuroscienceneurodegenerative diseasesbiochemistrycell metabolism

Centella Asiatica Alters Metabolic Pathways Associated With Alzheimer’s Disease in the 5Xfad Mouse Model of ß-Amyloid Accumulation. Frontiers in Pharmacology (2021)

Alex B. SpeersManuel García-JaramilloAlicia FerynDonald G. MatthewsTalia LichtenbergMaya CarusoKirsten M. WrightJoseph F. QuinnJan F. StevensClaudia S. MaierAmala SoumyanathNora E. Gray

1
2
10 / page