Faculty

Institution

Unit

Venue

Aleksandar Poleksic

University of Northern Iowa

Affiliations

College of Humanities, Arts & Sciences

Department Of Computer Science

Department of Humanities

University of Northern Iowa

NoneAleksandar Poleksic is currently serving as a College Of Humanities, Arts & Sciences faculty at University of Northern Iowa.

Honors

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Experiences

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Education

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Aleksandar Poleksic

University of Northern Iowa

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protein science molecular biology protein structure protein structure prediction bioinformatics structural biology biomolecular structure computational biology systems biology structural molecular biology structural bioinformatics protein modeling protein bioinformatics data science molecular informatics sequence alignment drug discovery biomedical informatics target prediction medicine machine learning drug targets biomolecular structure prediction network analysis clinical research scientific data proteome research scientific data management drug repositioning biological networks knowledge discovery scientific computing genome biology computational statistics experimental medicine medicinal research pharmacological research numerical mathematics numerical algorithms biomedical data science target identification cold-start problem collaborative filtering clinical data clinical databases research data management rare event estimation predictive toxicology system pharmacology spatial verification pathway analysis profiling technique computational biophysics sequence analysis curve modeling geometry processing sparse representations regularization (mathematics) autoencoders matrix theory omics data integration drug repurposing drug target identification profile-profile scoring drug combinations novel chemicals drug-target associations fast method convergent island statistics statistical significance island method profile-profile alignment scores expected polynomial time distance constraint biomedical networks protein sequence alignments

Notable Scholarly Works

Notable Federal Grants

Collaborators

Retinal Transcriptomic Signatures in Sudden Acquired Retinal Degeneration Syndrome (Sards) and Cancer-Associated Retinopathy (Car). Animals (2026)

ocular diseaseophthalmologyretinal transcriptomic signaturesmolecular neurodegenerationglaucomaophthalmology retinaretinacell biologyneuro-ophthalmologycancer-associated retinopathy

Fast Dual-Regularized Autoencoder for Sparse Biological Data. EPiC series in computing (2024)

deep learningregularization (mathematics)machine learningcomputational biologyautoencodersdata sciencemachine learning researchsparse representationsdual-regularized autoencoderneural network (machine learning)biomedical informatics

Optimization in Hyperbolic Space - Applications to Drug-Target Interaction Prediction. Lecture notes in computer science (2024)

computational sciencecomputational chemistrymodel selectiondrug discoverymolecular dockingdrug targetscomputational biologymolecular informaticsmathematical biosciencetarget predictionsystems biologyapplied mathematicsrational drug designhyperbolic spacehit identification

Utilizing Comprehensive Biological Network to Improve Accuracy of Computational Drug Repurposing. (2024)

bioinformaticsdrug discoverycomputational biologybiological networkstheoretical biologydrug repositioningmolecular informaticsmathematical bioscienceimprove accuracymolecular biologysystems biologycomprehensive biological networkcomputational drug repurposingrational drug designbiomedical informatics

Hyperbolic Matrix Factorization Improves Prediction of Drug-Target Associations. Scientific Reports (2023)

pharmacologymodel selectiondrug discoverysystem pharmacologycomputational biologydrug targetsmolecular informaticstarget predictiondrug-target associationsbiomedical informatics

Overcoming Sparseness of Biomedical Networks to Identify Drug Repositioning Candidates. IEEE/ACM Transactions on Computational Biology and Bioinformatics (2021)

pharmacological researchnetwork sciencenetwork analysisbioinformaticsdrug discoverybiomedical networksbiological networksdrug repositioningdata sciencetarget predictionsystems biologybiomedical informatics

Heterogeneous Multi-Layered Network Model for Omics Data Integration and Analysis. Frontiers in Genetics (2020)

Bohyun LeeShuo ZhangAleksandar PoleksicLei Xie

geneticsdata integrationnetwork analysisbioinformaticsdata sciencesystems engineeringomics data integration

Hyperbolic Matrix Factorization Reaffirms the Negative Curvature of the Native Biological Space. bioRxiv (Cold Spring Harbor Laboratory) (2020)

matrix factorizationtheoretical biologygeometric analysisspectral theorynegative curvaturesystems biologylinear algebrabiosystemsmatrix theoryapplied mathematicsnative biological spacehyperbolic equations

Database of Adverse Events Associated With Drugs and Drug Combinations. Scientific Reports (2019)

Aleksandar PoleksicLei Xie

pharmacologyclinical databasesmedicinescientific datascientific data managementclinical researchdrug combinationsresearch data managementclinical data

Exploring Landscape of Drug-Target-Pathway-Side Effect Associations.. PubMed (2018)

Hansaim LimAleksandar PoleksicLei Xie

pharmacologyhealth sciencesmedicinepathway analysisclinical researchmedicinal researchexperimental medicine

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Aleksandar Poleksic

University of Northern Iowa

Affiliations

College of Humanities, Arts & Sciences

Department Of Computer Science

Department of Humanities

University of Northern Iowa

NoneAleksandar Poleksic is currently serving as a College Of Humanities, Arts & Sciences faculty at University of Northern Iowa.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Aleksandar Poleksic

University of Northern Iowa

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Retinal Transcriptomic Signatures in Sudden Acquired Retinal Degeneration Syndrome (Sards) and Cancer-Associated Retinopathy (Car). Animals (2026)

ocular diseaseophthalmologyretinal transcriptomic signaturesmolecular neurodegenerationglaucomaophthalmology retinaretinacell biologyneuro-ophthalmologycancer-associated retinopathy

Fast Dual-Regularized Autoencoder for Sparse Biological Data. EPiC series in computing (2024)

Optimization in Hyperbolic Space - Applications to Drug-Target Interaction Prediction. Lecture notes in computer science (2024)

Utilizing Comprehensive Biological Network to Improve Accuracy of Computational Drug Repurposing. (2024)

Hyperbolic Matrix Factorization Improves Prediction of Drug-Target Associations. Scientific Reports (2023)

pharmacologymodel selectiondrug discoverysystem pharmacologycomputational biologydrug targetsmolecular informaticstarget predictiondrug-target associationsbiomedical informatics

Overcoming Sparseness of Biomedical Networks to Identify Drug Repositioning Candidates. IEEE/ACM Transactions on Computational Biology and Bioinformatics (2021)

Heterogeneous Multi-Layered Network Model for Omics Data Integration and Analysis. Frontiers in Genetics (2020)

Bohyun LeeShuo ZhangAleksandar PoleksicLei Xie

geneticsdata integrationnetwork analysisbioinformaticsdata sciencesystems engineeringomics data integration

Hyperbolic Matrix Factorization Reaffirms the Negative Curvature of the Native Biological Space. bioRxiv (Cold Spring Harbor Laboratory) (2020)

Database of Adverse Events Associated With Drugs and Drug Combinations. Scientific Reports (2019)

Aleksandar PoleksicLei Xie

pharmacologyclinical databasesmedicinescientific datascientific data managementclinical researchdrug combinationsresearch data managementclinical data

Exploring Landscape of Drug-Target-Pathway-Side Effect Associations.. PubMed (2018)

Hansaim LimAleksandar PoleksicLei Xie

pharmacologyhealth sciencesmedicinepathway analysisclinical researchmedicinal researchexperimental medicine

1
2
3
4
10 / page