Faculty

Institution

Unit

Venue

Alec Hirsch

Oregon Health & Science University

Affiliations

Division Of Pathobiology And Immunology

NoneAlec Hirsch is currently serving as a Division Of Pathobiology And Immunology faculty at Oregon Health & Science University.

Honors

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Experiences

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Education

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Alec Hirsch

Oregon Health & Science University

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virology virus research infectious diseases medical virology immunology viral pathogenesis virus-host interactions antiviral research infectious diseases (medical specialty) molecular virology general virology cell biology immune responses immunity (medicine) medicine tropical medicine viral genetics antiviral compounds gene expression maternal health medicinal chemistry mammalian biology viral replication antiviral drug development vaccine development antiviral drugs zika virus infection veterinary medicine medicinal research virus eradication arbovirus maternal immunization virus transmission molecular cell biology experimental medicine viral evolution small rna microrna detection emerging infectious diseases west nile virus powassan virus cell death nature animal science adaptive immune system antiviral responses vaccine targets viral diagnostics antiviral therapy dengue virus infection nonhuman primates avian biology avian medicine vascular biology experimental biology traditional medicines obstetrics drug development g protein-coupled receptor virus gene apoptosis andrology dopamine aging-associated diseases host-microbe interactions unfolded protein response placental dysfunction pregnant rhesus macaques microrna screen wnt signaling pathway flavivirus infection age-related vulnerability nile virus key role cholesterol-rich membrane microdomains high-content assay

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Zika Virus-Like Particle Vaccine Mitigates Early Pregnancy Loss in Rhesus Macaques. bioRxiv (Cold Spring Harbor Laboratory) (2025)

vaccinesreproductive immunologymedical virologyrhesus macaquesvaccine developmentmaternal healthvirologymaternal immunizationvaccinationinfectious diseasesvaccine researchinfectious diseases (medical specialty)

Comparative Analysis of Two Zika Virus Isolates in a Rhesus Macaque Pregnancy Model. Viruses (2025)

virus researchmedical virologyepidemiologycomparative analysisvirologyinfectious diseasesvirus transmissionzika virus isolatesinfectious diseases (medical specialty)emerging infectious diseases

Effect of Obesity on the Acute Response to Sars-Cov-2 Infection and Development of Post-Acute Sequelae of Covid-19 (Pasc) in Nonhuman Primates. PLoS Pathogens (2025)

obesity medicinecommunicable diseasessars-cov-2covid-19medical virologyacute responseepidemiologycovid-19 pandemicviral pathogenesissars-cov-2 infectionobesityinfectious diseasesnonhuman primatesvirus transmission

Effects of West Nile Virus on Behavioral and Cognitive Performance, Cortical Aβ Pathology, Viral Loads, and Immune Measures of Middle-Aged Nl-G-F/E3 and Nl-G-F/E4 Mice. Frontiers in Aging Neuroscience (2025)

neurologyneuropsychologyneurodegenerative diseasesneurovirologymedical virologywest nile virusneuroimmunologynl-g-f/e4 miceimmune measurescognitive impairmentmolecular neurodegenerationneuroscience of agingbrain functionpsychoneuroimmunologyneurosciencebehavioral neuroscience

Enantioselective Chemical Probe for Chikungunya Nsp2 Helicase With Antialphaviral Activity. ACS Infectious Diseases (2025)

medicinal chemistryvirus researchantiviral researchantiviral compoundsantiviral drugsbiotechnologychikungunya nsp2 helicasechemical biologyantiviral drug developmentvirologychemical scienceschemistryvirus eradicationbiochemistry

Exploration of 4′-Fluoro Fleximer Nucleoside Analogues as Potential Broad-Spectrum Antiviral Agents. Bioorganic & Medicinal Chemistry (2025)

Kyle A DavisJason K SmithJessica L SmithMeareg AmareMeghan V DiefenbacherPeter HalfmannTimothy P SheahanAlec J HirschKatherine L Seley-Radtke

medicinal chemistryvirus researchantiviral researchpharmaceutical chemistryantiviral compoundsbioorganic chemistryantiviral drugsdrug discoverymolecular biologyantiviral therapyantiviral drug developmentbiochemistry

Exposure to Covid-19 Virus-Like Particles Modulates Firing Patterns of Cortical Neurons in the Mouse Brain. Communications Biology (2025)

virus researchsars-cov-2viral persistencevirus-host interactionscovid-19neurovirologymedical virologymouse brainviral pathogenesiscortical neuronsvirologyinfectious diseasesvirus transmissionneuroscienceneurons

Intracranial Injection of Genetically Modified, Mosquito Non-Transmissible Zika Virus: Safety in Primates and Ramifications for Brain Tumor Therapy. Cell Reports Medicine (2025)

vaccinesneurologyvector borne diseaseneurovirologytropical medicineneuroimmunologyvirus eradicationbrain tumor therapyinfectious diseasesintracranial injectionarbovirusinfectious diseases (medical specialty)

Novel Tricycle Expanded Purine Nucleosides With Pan-Viral Activity. Bioorganic & Medicinal Chemistry (2025)

virus researchantiviral researchsmall moleculesantiviral compoundsantiviral drugsbiomolecular engineeringvirologypurine nucleosides

Role of Non-Human Primate Models in Accelerating Research and Developing Countermeasures Against Zika Virus Infection. The Lancet Microbe (2025)

Amanda LiLark L CoffeyEmma L MohrJessica RaperAnn ChahroudiKarla K AusderauMatthew T AliotaThomas C FriedrichAnn M MitzeyMichelle R KoenigThaddeus G GolosHannah K JaegerVictoria H J RobertsJamie O LoJessica L SmithAlec J HirschDaniel N StreblowChristina M NewmanDavid H O'ConnorEve M LackritzKoen K A Van RompayKristina M Adams Waldorf

public healthvirus researchinfectious disease modellingvirus infectioninfection controlepidemiologyvirus epidemiologyinfectious diseasesnon-human primate models

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Alec Hirsch

Oregon Health & Science University

Affiliations

Division Of Pathobiology And Immunology

NoneAlec Hirsch is currently serving as a Division Of Pathobiology And Immunology faculty at Oregon Health & Science University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Alec Hirsch

Oregon Health & Science University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Zika Virus-Like Particle Vaccine Mitigates Early Pregnancy Loss in Rhesus Macaques. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Comparative Analysis of Two Zika Virus Isolates in a Rhesus Macaque Pregnancy Model. Viruses (2025)

virus researchmedical virologyepidemiologycomparative analysisvirologyinfectious diseasesvirus transmissionzika virus isolatesinfectious diseases (medical specialty)emerging infectious diseases

Effect of Obesity on the Acute Response to Sars-Cov-2 Infection and Development of Post-Acute Sequelae of Covid-19 (Pasc) in Nonhuman Primates. PLoS Pathogens (2025)

Enantioselective Chemical Probe for Chikungunya Nsp2 Helicase With Antialphaviral Activity. ACS Infectious Diseases (2025)

Exploration of 4′-Fluoro Fleximer Nucleoside Analogues as Potential Broad-Spectrum Antiviral Agents. Bioorganic & Medicinal Chemistry (2025)

Kyle A DavisJason K SmithJessica L SmithMeareg AmareMeghan V DiefenbacherPeter HalfmannTimothy P SheahanAlec J HirschKatherine L Seley-Radtke

Exposure to Covid-19 Virus-Like Particles Modulates Firing Patterns of Cortical Neurons in the Mouse Brain. Communications Biology (2025)

Intracranial Injection of Genetically Modified, Mosquito Non-Transmissible Zika Virus: Safety in Primates and Ramifications for Brain Tumor Therapy. Cell Reports Medicine (2025)

Novel Tricycle Expanded Purine Nucleosides With Pan-Viral Activity. Bioorganic & Medicinal Chemistry (2025)

virus researchantiviral researchsmall moleculesantiviral compoundsantiviral drugsbiomolecular engineeringvirologypurine nucleosides

Role of Non-Human Primate Models in Accelerating Research and Developing Countermeasures Against Zika Virus Infection. The Lancet Microbe (2025)

public healthvirus researchinfectious disease modellingvirus infectioninfection controlepidemiologyvirus epidemiologyinfectious diseasesnon-human primate models

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6
10 / page