Faculty

Institution

Unit

Venue

Alan Leff

Professor of Medicine

University of Chicago

Affiliations

Medicine, Department of

Alan Leff is currently serving as a Medicine, Department Of Professor of Medicine at University of Chicago.

Honors

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Experiences

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Education

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Alan Leff

University of Chicago

Professor of Medicine

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respiratory medicine physiology pharmacology immunology animal physiology cell biology membrane biology cellular physiology mammalian biology molecular physiology applied physiology respiration (physiology) veterinary medicine inflammation mammalian physiology cardiology cell signaling respiratory neurobiology veterinary physiology exercise physiology liver physiology electrophysiology human eosinophils human physiology adhesion cell adhesion pulmonary pharmacology circulatory physiology medicinal research vascular biology avian biology protein science enzyme inhibition animal science clinical immunology pulmonary diseases molecular cell biology molecular immunology innate immune system guinea pigs guinea pig trachealis protein secretion molecular regulation clinical physiology cell migration hemostasis acute lung injury biological chemistry respiratory toxicology muscle function protein function human neutrophils secretory group physiological research protein transport cytokines in vivo systems translational physiology immunochemistry eosinophilic disorders cell regulation veterinary research canine tracheal muscle veterinary behavioral medicine cardiomyopathy endothelial dysfunction cellular immune responses chronic antigen challenge passive sensitization airway hyperresponsiveness isocapnic hyperpnea eosinophil migration bronchomotor tone hyperpnea-induced bronchoconstriction focal clustering acetylcholinesterase activity medicine asthma allergy

Notable Scholarly Works

Notable Federal Grants

Collaborators

Tuberculosis. Oxford University Press eBooks (2024)

Christian W. McMillen

Abstract 13483: Peptide Inhibition of Pten Improves Metabolic Recovery and Outcomes in a Murine Cardiac Arrest Model. Circulation (2015)

Xiangdong ZhuHuashan WangYouhua WangJing LiAlan R LeffTerry L Vanden Hoek

survival analysistherapeutic efficacymedicinepeptide inhibitionpharmacokineticscirculatory physiologymembrane biologyinflammationcardiologycellular physiologyregenerative medicinedrug targetingphysiologycardiovascular physiologypharmacologyapplied physiologycardiovascular researchmedicinal researchcardiac arrest

Abstract 13557: Regulation of Pbef Release by Nad Glycohydrolase Cd38. Circulation (2015)

Xiangdong ZhuAngelo MelitonJing LiYouhua WangMengqi ZhuAlan R LeffTerry L Vanden Hoek

physiologycardiologypbef releasecardiovascular physiologypharmacologycardiovascular researchcell signalingmetabolic regulationmolecular regulationenzymesmolecular physiologycirculatory physiologymembrane biologybiochemistry

A Novel Pharmacological Strategy by Pten Inhibition for Improving Metabolic Resuscitation and Survival After Mouse Cardiac Arrest. AJP Heart and Circulatory Physiology (2015)

Jing LiHuashan WangQiang ZhongXiangdong ZhuSy-Jou ChenYuanyu QianJim CostakisGabrielle BunneyDavid G. BeiserAlan R. LeffE. Douglas LewandowskiJ. Michael ÓDonnellTerry L. Vanden Hoek

cardiologypulmonary pharmacologypharmacologyemergency medicinedrug metabolismanimal physiologyreperfusion injurytranslational pharmacologymolecular pharmacologymetabolic resuscitationmouse cardiac arrestexperimental pharmacologypten inhibitioncirculatory physiologyhealth sciencescardiovascular pharmacology

Abstract 17773: Peptide Inhibition of Pten Increases Mouse Survival After Sudden Cardiac Arrest. Circulation (2014)

Xiangdong ZhuHuashan WangYouhua WangJing LiAlan R LeffTerry L Vanden Hoek

physiologycardiologymedicinecardiac arrestpharmacologypeptidespeptide inhibitionsudden cardiac arrestcardiovascular researchdeath studiesrespiratory medicinecirculatory physiologycardiovascular disease

Abstract 178: The Early Resuscitation Protein Pbef is Released From Human Neutrophils via an Unconventional Pathway. Circulation (2014)

Xiangdong ZhuAngelo MelitonJing LiAndrew BellinoMengqi ZhuHuashan WangAlan R LeffTerry L Vanden Hoek

cardiologyimmunologyunconventional pathwayemergency medicinereperfusion injurymammalian biologyinnate immune systemhuman neutrophilscritical carecirculatory physiologyresuscitation

Asthma in Pregnancy. CRC Press eBooks (2014)

Paul Greenberger

cardiologymedicinepulmonary diseasesemergency medicineasthmahigh-risk pregnanciesobstetrics and gynaecologymaternal healthrespiratory medicineneonatologyhealth sciencespregnancy hypertension

Attenuation of Lipopolysaccharide-Induced Lung Vascular Stiffening by Lipoxin Reduces Lung Inflammation. American Journal of Respiratory Cell and Molecular Biology (2014)

Fanyong MengIsa MambetsarievYufeng TianYvonne BeckhamAngelo MelitonAlan LeffMargaret L. GardelMichael J. AllenKonstantin G. BirukovAnna A. Birukova

physiologypharmacologyrespiratory toxicologycellular physiologyrespiratory neurobiologymammalian biologymolecular biologyrespiratory medicinemembrane biologyinflammation

Tat-Protein Blockade During Ischemia/Reperfusion Reveals Critical Role for P85 Pi3K-Pten Interaction in Cardiomyocyte Injury. PLoS ONE (2014)

Xiangdong ZhuZuo-Hui ShaoChangqing LiJing LiQiang ZhongJonathan LearoydAngelo MelitonLucille MelitonAlan R. LeffTerry L. Vanden Hoek

protein functioncell signalingliver physiologycell biologyprotein transportcardiomyopathymembrane biologyinflammationcardiologycellular physiologyregenerative medicinereperfusion injurycardiomyocyte injurymolecular physiologycellular biochemistrycardiac musclephysiologypharmacologytat-protein blockadecirculatory physiology

Abstract 18534: Tat-Protein Blockade of Pten After Cardiac Ischemia is Highly Protective. Circulation (2013)

Xiangdong ZhuZuohui ShaoHuashan WangJing LiAngelo MelitonSy-Jou ChenChangqing LiAlan R LeffTerry L Vanden Hoek

therapeutic efficacyendocrinologyhealth sciencesinflammationcardiologycerebrovascular diseasecardiovascular functionregenerative medicinephysiologycardiovascular physiologypharmacologycardiac ischemiaapplied physiologycardiovascular researchrenal functiontat-protein blockadepharmacotherapyrespiratory medicinemedicinal researchcardiovascular disease

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Alan Leff

Professor of Medicine

University of Chicago

Affiliations

Medicine, Department of

Alan Leff is currently serving as a Medicine, Department Of Professor of Medicine at University of Chicago.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Alan Leff

University of Chicago

Professor of Medicine

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Tuberculosis. Oxford University Press eBooks (2024)

Christian W. McMillen

Abstract 13483: Peptide Inhibition of Pten Improves Metabolic Recovery and Outcomes in a Murine Cardiac Arrest Model. Circulation (2015)

Xiangdong ZhuHuashan WangYouhua WangJing LiAlan R LeffTerry L Vanden Hoek

Abstract 13557: Regulation of Pbef Release by Nad Glycohydrolase Cd38. Circulation (2015)

Xiangdong ZhuAngelo MelitonJing LiYouhua WangMengqi ZhuAlan R LeffTerry L Vanden Hoek

A Novel Pharmacological Strategy by Pten Inhibition for Improving Metabolic Resuscitation and Survival After Mouse Cardiac Arrest. AJP Heart and Circulatory Physiology (2015)

Jing LiHuashan WangQiang ZhongXiangdong ZhuSy-Jou ChenYuanyu QianJim CostakisGabrielle BunneyDavid G. BeiserAlan R. LeffE. Douglas LewandowskiJ. Michael ÓDonnellTerry L. Vanden Hoek

Abstract 17773: Peptide Inhibition of Pten Increases Mouse Survival After Sudden Cardiac Arrest. Circulation (2014)

Xiangdong ZhuHuashan WangYouhua WangJing LiAlan R LeffTerry L Vanden Hoek

Abstract 178: The Early Resuscitation Protein Pbef is Released From Human Neutrophils via an Unconventional Pathway. Circulation (2014)

Xiangdong ZhuAngelo MelitonJing LiAndrew BellinoMengqi ZhuHuashan WangAlan R LeffTerry L Vanden Hoek

cardiologyimmunologyunconventional pathwayemergency medicinereperfusion injurymammalian biologyinnate immune systemhuman neutrophilscritical carecirculatory physiologyresuscitation

Asthma in Pregnancy. CRC Press eBooks (2014)

Paul Greenberger

cardiologymedicinepulmonary diseasesemergency medicineasthmahigh-risk pregnanciesobstetrics and gynaecologymaternal healthrespiratory medicineneonatologyhealth sciencespregnancy hypertension

Attenuation of Lipopolysaccharide-Induced Lung Vascular Stiffening by Lipoxin Reduces Lung Inflammation. American Journal of Respiratory Cell and Molecular Biology (2014)

Fanyong MengIsa MambetsarievYufeng TianYvonne BeckhamAngelo MelitonAlan LeffMargaret L. GardelMichael J. AllenKonstantin G. BirukovAnna A. Birukova

physiologypharmacologyrespiratory toxicologycellular physiologyrespiratory neurobiologymammalian biologymolecular biologyrespiratory medicinemembrane biologyinflammation

Tat-Protein Blockade During Ischemia/Reperfusion Reveals Critical Role for P85 Pi3K-Pten Interaction in Cardiomyocyte Injury. PLoS ONE (2014)

Xiangdong ZhuZuo-Hui ShaoChangqing LiJing LiQiang ZhongJonathan LearoydAngelo MelitonLucille MelitonAlan R. LeffTerry L. Vanden Hoek

Abstract 18534: Tat-Protein Blockade of Pten After Cardiac Ischemia is Highly Protective. Circulation (2013)

Xiangdong ZhuZuohui ShaoHuashan WangJing LiAngelo MelitonSy-Jou ChenChangqing LiAlan R LeffTerry L Vanden Hoek

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5
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Julian Solway

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University of Chicago

respiratory medicine

pulmonary diseases

Alexander Verin

Institution

Augusta University

vascular biology

membrane biology

Jacob I Sznajder

Institution

Northwestern University

respiratory medicine

physiology

Richard Minshall

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endothelial cell biology

endothelial dysfunction

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free radical biology

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endocrinology

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health science

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