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Alan L. Landay

Rush University

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Rush Center For Integrated Microbiome And Chronobiology Research

Alan L. Landay is a High Senior Professor at Rush University. His research focuses on HIV immunology, infectious diseases, and clinical virology, with particular emphasis on immune responses, virus research, and public health epidemiology. His latest work includes developing and validating a quantitative Orthopoxvirus immunoassay to differentiate serological responses to Mpox infection versus vaccination, and investigating the opposite roles of IL-32 isoforms in promoting vascular calcification in people with HIV. He also leads studies on the effects of pitavastatin on epigenetic aging biomarkers, associations between circulating T cell subsets and endothelial function, and gut microbiome influences on inflammation and cardiovascular profiles in HIV. His recent publications appear in EBioMedicine, Cells, Clinical Infectious Diseases, and The Journal of Infectious Diseases, reflecting his international collaborations in advancing HIV-related cardiovascular and immunological research.

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Alan L. Landay

Rush University

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immunology hiv infectious diseases virology immune responses clinical immunology public health health sciences immunity (medicine) medical virology clinical microbiology virus research hematology infection control antiviral research general virology clinical epidemiology respiratory medicine adaptive immune system inflammation medicinal research immunopathology viral pathogenesis hiv infection virus-host interactions cellular immune responses vascular biology antiviral therapy emerging infectious diseases human retrovirus veterinary medicine cytokines clinical infectious disease antiretroviral therapy t-regulatory cell cardiovascular research disease transmission mucosal immunology antiviral responses innate immune system molecular immunology virus epidemiology chronic viral infections cellular therapy laboratory immunology medical microbiology viral diagnostics immune dysregulation lymphocyte development human immunodeficiency virus reproductive immunology clinical evidence sexual health viral genetics chronic inflammation disease progression female genital tract thrombosis viral replication immunologic diseases immune activation infectious disease modelling experimental medicine gut microbes hiv-infected women viral persistence active antiretroviral therapy hiv-infected individuals carotid artery atherosclerosis flow cytometry genital tract hiv-infected patients gut microbiota t-cell activation immune reconstitution microbial translocation

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract P1160: Gut Microbiota, Circulating Inflammatory Markers, and Cardiac Dysfunction in Women Living With Hiv. Circulation (2025)

Zheng WangSanyog ShitoleAnjali SharmaDavid HannaBrandilyn Peters-SamuelsonTao WangWendy PostAlan Landaykathleen weberAudrey FrenchDANIEL MERENSTEINSabina HaberlenAlan HinderliterIgho OfotokunClaudia MartinezJulie SchexnayderJason LazarDeborah GustafsonKathryn AnastosRob KnightRobert KaplanRobert BurkJORGE KIZERQibin Qi

public healthhivcardiac dysfunctiongut microbiotainflammatory markers

Antibody Responses Are Sustained 2 Years Post-Mpox Infection but Not Following Modified Vaccinia Ankara–Bavarian Nordic Vaccination. Open Forum Infectious Diseases (2025)

Associations Between the Gut Microbiome, Inflammation, and Cardiovascular Profiles in People With Human Immunodeficiency Virus. The Journal of Infectious Diseases (2025)

Rachel MacCannJunhui LiAlejandro Abner Garcia LeonRiya NegiDana AlalwanWillard TinagoPadraig McGettrickAoife G CotterAlan LandayCaroline SabinPaul W O’ToolePatrick W MallonPadraig McGettrickElena Alvarez BarcoWillard TinagoAlejandro Garcia LeonAoife McDermottTara McGintyAoife G CotterAlan MackenPatrick W G MallonEoin KavanaghGeraldine McCarthyGerard SheehanJohn LambertWilliam PowderlyJuliet CompstonCaroline Sabin

hivinfectious diseasesgut microbiomecardiovascular profilesinflammation

Associations of Circulating T Cell Subsets With Endothelial Function: The Multi-Ethnic Study of Atherosclerosis. American Journal of Physiology-Heart and Circulatory Physiology (2025)

Theodore M. DeConneColleen M. SitlaniKevin P. DeckerJoseph A. DelaneyBruce M. PsatyMargaret F. DoylePetra BuzkovaAlan L. LandaySally A. HuberTimothy M. HughesDavid HerringtonJingzhong DingNels C. Olson

physiologycardiovascular physiologyatherosclerosisendothelial functionmulti-ethnic studyt-cell subsetscirculatory physiology

Associations of Immune Cell Subsets With Coronary Artery Calcium Incidence and Progression in the Multi‐Ethnic Study of Atherosclerosis. Journal of the American Heart Association (2025)

immunologyimmune cell subsetsmulti‐ethnic studycardiovascular researchepidemiologyatherosclerosisvascular biologyinflammatory markerscardiovascular diseaseimmune responsescoronary artery diseaseimmunity (medicine)inflammation

Automated Screening of Electronic Medical Records to Detect the Next Pandemic. American Journal of Respiratory and Critical Care Medicine (2025)

communicable diseasesclinical dataautomated screeningpublic health preparednessdisease surveillanceclinical databasescovid-19next pandemicepidemiologyepidemic intelligencehealth informaticshealth information scienceelectronic health recordselectronic medical recordsinfectious diseaseshealth technologydigital healthinfectious diseases (medical specialty)

Compromised Intestinal Barrier Resilience to Disruption in People With Hiv. The Journal of Infectious Diseases (2025)

Maliha W ShaikhShalini SinghLeila B GironLijuan ZhangShivanjali ShankaranPhillip A EngenMichelle VillanuevaAshish Arunkumar SharmaRafick-Pierre SekalyAlan LandayAli KeshavarzianMohamed Abdel-Mohsen

hivintestinal barrier resilienceresilienceinfectious diseases

Development and Validation of a Quantitative Orthopoxvirus Immunoassay to Evaluate and Differentiate Serological Responses to Mpox Infection and Vaccination. EBioMedicine (2025)

Joanne ByrneGurvin SainiAlejandro Garcia-LeonDana AlalwanPeter DoranAlan LandayLiem Binh Luong NguyenCathal O'BroinStefano SavinelliJane A O'HalloranAoife CotterMary HorganChristine KellyCorinna SadlierEoghan de BarraVirginie GautierPatrick W G MallonEoin R Feeney

immunologyvaccinesquantitative orthopoxvirus immunoassayserological responsesvaccinationinfectious diseasesviral diagnostics

Effect of Pitavastatin on Epigenetic Aging Biomarkers in People With Hiv: Pilot Substudy of the Reprieve Trial. Clinical Infectious Diseases (2025)

hivmedicineageingbiomarkersexperimental gerontologyreprieve trialbiogerontologypilot substudyaging cellepigenetic aging biomarkersepigeneticshealth sciencestranslational medicine

Epigenetic Aging and Treatment Response to Semaglutide in the Slim Liver Study. Research Square (2025)

pharmacologybiogerontologyaging cellhepatologyepigenetics

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Alan L. Landay

Rush University

Affiliations

News & Events

Rush Center For Integrated Microbiome And Chronobiology Research

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Alan L. Landay

Rush University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract P1160: Gut Microbiota, Circulating Inflammatory Markers, and Cardiac Dysfunction in Women Living With Hiv. Circulation (2025)

public healthhivcardiac dysfunctiongut microbiotainflammatory markers

Antibody Responses Are Sustained 2 Years Post-Mpox Infection but Not Following Modified Vaccinia Ankara–Bavarian Nordic Vaccination. Open Forum Infectious Diseases (2025)

Associations Between the Gut Microbiome, Inflammation, and Cardiovascular Profiles in People With Human Immunodeficiency Virus. The Journal of Infectious Diseases (2025)

hivinfectious diseasesgut microbiomecardiovascular profilesinflammation

Associations of Circulating T Cell Subsets With Endothelial Function: The Multi-Ethnic Study of Atherosclerosis. American Journal of Physiology-Heart and Circulatory Physiology (2025)

physiologycardiovascular physiologyatherosclerosisendothelial functionmulti-ethnic studyt-cell subsetscirculatory physiology

Associations of Immune Cell Subsets With Coronary Artery Calcium Incidence and Progression in the Multi‐Ethnic Study of Atherosclerosis. Journal of the American Heart Association (2025)

Automated Screening of Electronic Medical Records to Detect the Next Pandemic. American Journal of Respiratory and Critical Care Medicine (2025)

Compromised Intestinal Barrier Resilience to Disruption in People With Hiv. The Journal of Infectious Diseases (2025)

Maliha W ShaikhShalini SinghLeila B GironLijuan ZhangShivanjali ShankaranPhillip A EngenMichelle VillanuevaAshish Arunkumar SharmaRafick-Pierre SekalyAlan LandayAli KeshavarzianMohamed Abdel-Mohsen

hivintestinal barrier resilienceresilienceinfectious diseases

Development and Validation of a Quantitative Orthopoxvirus Immunoassay to Evaluate and Differentiate Serological Responses to Mpox Infection and Vaccination. EBioMedicine (2025)

immunologyvaccinesquantitative orthopoxvirus immunoassayserological responsesvaccinationinfectious diseasesviral diagnostics

Effect of Pitavastatin on Epigenetic Aging Biomarkers in People With Hiv: Pilot Substudy of the Reprieve Trial. Clinical Infectious Diseases (2025)

hivmedicineageingbiomarkersexperimental gerontologyreprieve trialbiogerontologypilot substudyaging cellepigenetic aging biomarkersepigeneticshealth sciencestranslational medicine

Epigenetic Aging and Treatment Response to Semaglutide in the Slim Liver Study. Research Square (2025)

pharmacologybiogerontologyaging cellhepatologyepigenetics

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