Faculty

Institution

Unit

Venue

Ahmed Chadli

Associate Professor

Augusta University

Affiliations

Medical College of Georgia

Biochemistry & Molecular Biology

Department of Medicine

Ahmed Chadli is currently serving as a Biochemistry & Molecular Biology Associate Professor at Augusta University.

Honors

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Experiences

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Education

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Ahmed Chadli

Augusta University

Associate Professor

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pharmacology oncology cancer biology molecular biology biochemistry cancer research medicinal research immunology tumor biology cancer immunotherapy biological chemistry protein science cancer treatment cell signaling endocrinology tumor targeting gene expression redox biology cancer care molecular regulation cell regulation protein structure molecular physiology cellular biochemistry anti-cancer agents molecular cancer cellular therapy cell death oncogenes tumor suppressors protein function therapeutic efficacy cellular physiology free radical biology receptor (biochemistry) cancer genomics apoptosis cancer genetics cancer cell death medical mycology mammalian biology respiratory medicine biomolecular interactions host factors protein genetics key site pathway analysis signaling pathways gene regulation metabolic regulation transcription regulation angiology arterial disease cellular biology protein chemistry hla typing glucocorticoids functional regulation renal pathophysiology renal function clinical pharmacology carboxyl terminus heat shock metastatic cascade granulocytic myeloid spatiotemporal tumour n-terminal domain proximity first step progesterone receptor syngeneic mouse model tumor cells steroid receptors glucocorticosteroid-dependent promoter novel regulator multiple domains full-length protein pathology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Natural Cyclic Peptides: Synthetic Strategies and Biomedical Applications. Biomedicines (2025)

Devan BuchananShogo MoriAhmed ChadliSiva S. Panda

medicinal chemistrybiomedical researchpeptidespeptide therapeuticspeptide synthesisbiosynthesisnatural productspeptide librarynatural cyclic peptidespeptide sciencebioactive compoundsbiomedical applicationssynthetic biologysynthetic strategiesenzyme inhibitionpeptide engineeringbiomedical engineeringbiomolecular engineeringmolecular biologymedicinal researchnatural product research

Dual Activity of Minnelide Chemosensitize Basal/Triple Negative Breast Cancer Stem Cells and Reprograms Immunosuppressive Tumor Microenvironment. Scientific Reports (2024)

Fulya Koksalar AlkanAhmet Burak CaglayanHilmi Kaan AlkanElayne BensonYunus Emre GunduzOzge SensoySerdar DurdagiElbrus ZarbaliyevGreg DysonHadeel AssadAustin ShullAhmed ChadliHuidong ShiGurkan OzturkHasan Korkaya

cell researchcell biologytumor targetingstem cell researchcancer careanti-cancer agentsbreast cancertumor microenvironmentcancer biologydual activitycancer researchcancer treatmenttumor biologyimmunologypharmacologystem-cell therapyoncologycancer cellscellular therapy

Stress Biology: Complexity and Multifariousness in Health and Disease. Figshare (2024)

Mayer, Matthias P.Blair, LauraBlatch, Gregory L.Borges, Thiago J.Chadli, AhmedChiosis, Gabrielade Thonel, AurélieDinkova-Kostova, AlbenaEcroyd, HeathEdkins, Adrienne L.Eguchi, TakanoriFleshner, MonikaFoley, Kevin P.Fragkostefanakis, SotiriosGestwicki, JasonGoloubinoff, PierreHeritz, Jennifer A.Heske, Christine M.Hibshman, Jonathan D.Joutsen, JennyLi, WeiLynes, MichaelMendillo, Marc L.Mivechi, NahidMokoena, FortunateOkusha, YukaPrahlad, VeenaRepasky, ElizabethSannino, SaraScalia, FedericaShalgi, ReutSistonen, LeaSontag, Emilyvan Oosten-Hawle, PatricijaVihervaara, AnniinaWickramaratne, AnushkaWang, Shawn Xiang YangZininga, Tawanda

endocrinologyhealth sciencesstress biology

Abstract 2272: Targeting the Chaperone Hsp90 to Activate the Immune System and Eradicate the Triple Negative Breast Cancer. Cancer Research (2023)

Nada EisaVincent M. CrowleyAsif ElahiVamsi K. KommalapatiHasan KorkayaAbdessamad DebbabBrian BlaggAhmed Chadli

immunologytumor targetingpharmacologycancer carecancer managementcancer researchcancer immunotherapycancer preventionbreast canceroncologyclinical researchmedicinal researchcancer treatmentcancer biologyimmune systemhealth sciences

Abstract 4606: Heat Shock Proteins in Immunosuppressive Tumor Microenvironment. Cancer Research (2023)

Fulya Koksalar AlkanJustin WilsonElayne BensonTulshi PatelVirginia McEvoyNate FrancoisEmma NguyenHilmi Kaan AlkanAhmed ChadliJason GestwickiHasan Korkaya

immunologyheat shock proteinscancer researchimmunosuppressive tumor microenvironmentoncologytumor microenvironmentcancer biologyimmunosuppressionhealth sciences

Capsaicin Binds the N-Terminus of Hsp90, Induces Lysosomal Degradation of Hsp70, and Enhances the Anti-Tumor Effects of 17-Aag (Tanespimycin). Scientific Reports (2023)

Chaitanya A. PatwardhanVamsi Krishna KommalapatiTaoufik LlbiyiDigvijay SinghEyad AlfaAnatolij HoruzskoHasan KorkayaSiva PandaChristopher A. ReillyVladimir PopikAhmed Chadli

tumor targetingcancer caremolecular canceranti-cancer agentscancer biologydermatologycancer researchanti-tumor effectstumor suppressorscancer immunotherapytherapeutic targetscancer treatmenttumor biologypharmacologygeneticsscientific dataoncologyoncogenesmedicinal research

Ccdc 2157502: Experimental Crystal Structure Determination. The Cambridge Structural Database (2023)

Rao, YuPalumbo, Chad T.Venkatesh, AmritKeener, MeganStevanato, GabrieleChauvin, Anne-SophieMenzildjian, GeorgesKuzin, SergeiYulikov, MaximJeschke, GunnarLesage, AnneMazzanti, MarinellaEmsley, Lyndon

biophysicsstructure elucidationcrystal researchcrystal diffraction studystructure determinationstructural chemistryccdc 2157502chemistrydeposited datasetcrystal engineeringchemical structurecrystal structurescrystallography

Enniatin a Analogues as Novel Hsp90 Inhibitors That Modulate Triple-Negative Breast Cancer. ACS Medicinal Chemistry Letters (2023)

Michael A. SerwetnykVincent M. CrowleyChristopher M. BrackettTrever R. CarterAsif ElahiVamsi Krishna KommalapatiAhmed ChadliBrian S. J. Blagg

medicinal chemistrypharmaceutical chemistrynovel therapiestriple-negative breast cancermedicinecancer careclinical chemistryanti-cancer agentsbreast cancercancer biologydrug deliveryhealth sciencescancer treatmentenzyme inhibitionpharmacologypharmacotherapydrug discoveryoncologymedicinal research

Enniatin a Inhibits the Chaperone Hsp90 and Unleashes the Immune System Against Triple-Negative Breast Cancer. iScience (2023)

Nada H EisaVincent M CrowleyAsif ElahiVamsi Krishna KommalapatiMichael A SerwetnykTaoufik LlbiyiSumin LuKashish KainthYasmeen JilaniDaniela MarascoAbdeljabar El AndaloussiSukyeong LeeFrancis T F TsaiPaulo C RodriguezDavid MunnEsteban CelisHasan KorkayaAbdessamad DebbabBrian BlaggAhmed Chadli

immunologytumor targetingtriple-negative breast cancerenzyme inhibitionpharmacologycancer researchcancer immunotherapycancer preventionbreast canceroncologymedicinal researchcancer treatmenttherapeutic efficacycancer biologyimmune systemhealth sciencesimmunotherapy

Targeting Trem1 Augments Antitumor T Cell Immunity by Inhibiting Myeloid-Derived Suppressor Cells and Restraining Anti–Pd-1 Resistance. Journal of Clinical Investigation (2023)

Ashwin AjithKenza MamouniDaniel D. HoruzskoAbu MusaAmiran K. DzutsevJennifer R. FangAhmed ChadliXingguo ZhuIryna LebedyevaGiorgio TrinchieriAnatolij Horuzsko

immunologyhivreceptorstumor targetingpharmacologymyeloid-derived suppressor cellscytokinestumor suppressorscancer immunotherapyclinical researchdrug targetingmedicinal researchclinical investigationtherapeutic efficacycellular therapyhealth sciencesimmunotherapy

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Ahmed Chadli

Associate Professor

Augusta University

Affiliations

Medical College of Georgia

Biochemistry & Molecular Biology

Department of Medicine

Ahmed Chadli is currently serving as a Biochemistry & Molecular Biology Associate Professor at Augusta University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Ahmed Chadli

Augusta University

Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Natural Cyclic Peptides: Synthetic Strategies and Biomedical Applications. Biomedicines (2025)

Devan BuchananShogo MoriAhmed ChadliSiva S. Panda

Dual Activity of Minnelide Chemosensitize Basal/Triple Negative Breast Cancer Stem Cells and Reprograms Immunosuppressive Tumor Microenvironment. Scientific Reports (2024)

Stress Biology: Complexity and Multifariousness in Health and Disease. Figshare (2024)

endocrinologyhealth sciencesstress biology

Abstract 2272: Targeting the Chaperone Hsp90 to Activate the Immune System and Eradicate the Triple Negative Breast Cancer. Cancer Research (2023)

Nada EisaVincent M. CrowleyAsif ElahiVamsi K. KommalapatiHasan KorkayaAbdessamad DebbabBrian BlaggAhmed Chadli

Abstract 4606: Heat Shock Proteins in Immunosuppressive Tumor Microenvironment. Cancer Research (2023)

Fulya Koksalar AlkanJustin WilsonElayne BensonTulshi PatelVirginia McEvoyNate FrancoisEmma NguyenHilmi Kaan AlkanAhmed ChadliJason GestwickiHasan Korkaya

immunologyheat shock proteinscancer researchimmunosuppressive tumor microenvironmentoncologytumor microenvironmentcancer biologyimmunosuppressionhealth sciences

Capsaicin Binds the N-Terminus of Hsp90, Induces Lysosomal Degradation of Hsp70, and Enhances the Anti-Tumor Effects of 17-Aag (Tanespimycin). Scientific Reports (2023)

Chaitanya A. PatwardhanVamsi Krishna KommalapatiTaoufik LlbiyiDigvijay SinghEyad AlfaAnatolij HoruzskoHasan KorkayaSiva PandaChristopher A. ReillyVladimir PopikAhmed Chadli

Ccdc 2157502: Experimental Crystal Structure Determination. The Cambridge Structural Database (2023)

Rao, YuPalumbo, Chad T.Venkatesh, AmritKeener, MeganStevanato, GabrieleChauvin, Anne-SophieMenzildjian, GeorgesKuzin, SergeiYulikov, MaximJeschke, GunnarLesage, AnneMazzanti, MarinellaEmsley, Lyndon

Enniatin a Analogues as Novel Hsp90 Inhibitors That Modulate Triple-Negative Breast Cancer. ACS Medicinal Chemistry Letters (2023)

Michael A. SerwetnykVincent M. CrowleyChristopher M. BrackettTrever R. CarterAsif ElahiVamsi Krishna KommalapatiAhmed ChadliBrian S. J. Blagg

Enniatin a Inhibits the Chaperone Hsp90 and Unleashes the Immune System Against Triple-Negative Breast Cancer. iScience (2023)

Targeting Trem1 Augments Antitumor T Cell Immunity by Inhibiting Myeloid-Derived Suppressor Cells and Restraining Anti–Pd-1 Resistance. Journal of Clinical Investigation (2023)

Ashwin AjithKenza MamouniDaniel D. HoruzskoAbu MusaAmiran K. DzutsevJennifer R. FangAhmed ChadliXingguo ZhuIryna LebedyevaGiorgio TrinchieriAnatolij Horuzsko

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