Afra Panahi

California State University, San Marcos

Affiliations

California State University, San Marcos

College Of Arts And Sciences

Department Of Chemistry

College of Science, Technology, Engineering and Mathematics

Department Of Chemistry And Biochemistry

NoneAfra Panahi is currently serving as a California State University, San Marcos faculty at California State University, San Marcos.

Honors

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Experiences

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Education

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Afra Panahi

California State University, San Marcos

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biophysics structural biology protein science molecular biology physical chemistry molecular biophysics computational chemistry biochemistry protein structure membrane biology materials science structural chemistry biomolecular structure structural molecular biology peptide science molecular structure lipid science membrane environment virology proteomics numerical simulations general virology virus research chemical sciences molecular science viral structural protein viral genetics molecular virology computational biophysics biophysical modeling dyslipidemia experimental biophysics genetic disorders transmembrane helices amyloid precursor protein conformational sampling interface science condensed matter membrane science mathematical bioscience theoretical biology membrane structure mathematical chemistry charge transport protein modeling protein transport virus-host interactions viral evolution molecular sorting advanced separations chemical thermodynamics phase separation venomics virus transmission hyperlipidemia lipid disorders molecular recognition protein genetics lipid chemistry lipid analysis lipoprotein metabolism peptide engineering peptide library mathematical biophysics site-specific structural information model membrane interface coarse-grained simulations critical size dependence domain formation ternary lipid mixtures implicit membrane model bilayer thickness specific binding charge state ph-dependent conformational transition line tension

Notable Scholarly Works

Notable Federal Grants

Collaborators

Molecular Dynamic Simulations of Membrane Transition in Cyclic Hexa-Peptides Using All-Atom and Coarse-Grained Models. Biophysical Journal (2021)

computational chemistryprotein designbiophysical chemistrymolecular modelsbiophysical reviewbiophysicspeptide sciencechemistrymolecular physicsmolecular modellingmolecular structuremolecular sciencebiomolecular engineeringpeptideschemical physicstheoretical chemistrymolecular biophysics

Conformational Sampling of Ph-Low Insertion Peptides in Multicomponent Bilyayers: Effects of Charged Lipids and Protonation States. Biophysical Journal (2020)

protein designpeptide engineeringbiophysical chemistrybiochemistrybiomolecular engineeringpeptidespeptide librarypeptide science

Impact of Cholesterol Concentration and Lipid Phase on Structure and Fluctuation of Amyloid Precursor Protein. The Journal of Physical Chemistry B (2020)

George A. PantelopulosAfra PanahiJohn E. Straub

liver physiologystructural chemistrybiochemistryphysical chemistryprotein sciencemembrane biologyamyloid precursor proteincholesterol concentrationmolecular biophysicsstructural biologycardiovascular researchprotein structuredyslipidemiahyperlipidemiabiophysicslipid sciencelipid phasechemical scienceslipid disordersexperimental biophysicsphysiology

M2 Amphipathic Helices Facilitate Ph-Dependent Conformational Transition in Influenza a Virus. Proceedings of the National Academy of Sciences (2020)

Hedieh TorabifardAfra PanahiCharles L. Brooks

geneticsviral structural proteingene expressionvirologystructural biologyviral evolutiongeneral virologyph-dependent conformational transitionprotein structurevirus-host interactionsvirus researchmolecular biologystructural molecular biologymolecular virologycell biologyviral geneticsprotein scienceinfluenza

Exploring the Impact of Proteins on the Line Tension of a Phase-Separating Ternary Lipid Mixture. The Journal of Chemical Physics (2019)

Asanga BandaraAfra PanahiGeorge A. PantelopulosTetsuro NagaiJohn E. Straub

biophysical chemistrymolecular sortingphysical chemistryprotein sciencebiomolecular structureproteomicsmolecular structurebiomolecular engineeringmolecular biophysicsline tensionchemical engineeringstructural biologychemical thermodynamicsphase separationbiophysicslipid scienceadvanced separationsmolecular sciencechemical sciences

Exploring the Structure and Stability of Cholesterol Dimer Formation in Multicomponent Lipid Bilayers. Journal of Computational Chemistry (2019)

Asanga BandaraAfra PanahiGeorge A. PantelopulosJohn E. Straub

computational chemistrystructural chemistrychemistrymembrane biologybiomolecular structuremolecular structuremembraneslipid analysisstructural biologycholesterol dimer formationlipidsstructural molecular biologydyslipidemialipoprotein metabolismlipid chemistrybiophysicsclinical lipidologylipid sciencemolecular biologymulticomponent lipid bilayers

Domain Interfaces Facilitate Protein Association and Aggregation in Multicomponent Lipid Bilayers. Biophysical Journal (2018)

Asanga Bandara Ekanayaka MudiyanselageAfra PanahiGeorge A. PantelopulosJohn E. Straub

membrane biologybiophysicsstructural biologymolecular biologycell biologymulticomponent lipid bilayersdomain interfacesmolecular biophysics

Molecular Basis for a Novel Systemic Form of Human Hereditary Apoa-I Amyloidosis With Vision Loss. bioRxiv (Cold Spring Harbor Laboratory) (2018)

Isabel MorgadoPierre-Raphael RothschildAfra PanahiJean-Claude AldigierAndrew G. BurwashMadhurima DasMagali ColombatThierry FrougetJean Philippe RerolleFrançois ParafNathalie Rioux-LeclercqJean-Michel GoujonCaroline BeugnetAntoine DurrbachDidier SamuelAntoine BrézinJohn E. StraubOlga GurskySophie Valleix

synthetic biologyophthalmologygenetic disordersmolecular evidencedisease gene identificationneurodegenerative diseasesprotein sciencegeneticshuman geneticsvision lossmolecular neurodegenerationnovel systemic formmolecular neurosciencegene expressionmammalian biologymolecular biologymedicinal researchnovel therapiesmolecular basis

Molecular Insights Into Human Hereditary Apolipoprotein A-I Amyloidosis Caused by the Glu34Lys Mutation. Biochemistry (2018)

Isabel MorgadoAfra PanahiAndrew G. BurwashMadhurima DasJohn E. StraubOlga Gursky

geneticshuman geneticsmolecular geneticsgenomicsgenetic disordersbiochemistrymolecular biologymolecular insightsprotein genetics

Critical Size Dependence of Domain Formation Observed in Coarse-Grained Simulations of Bilayers Composed of Ternary Lipid Mixtures. The Journal of Chemical Physics (2017)

George A. PantelopulosTetsuro NagaiAsanga BandaraAfra PanahiJohn E. Straub

computational chemistrymaterials sciencenumerical simulationsmathematical chemistrybiophysicscondensed matter physicsdeformationcoarse-grained simulationslipidsternary lipid mixturesapplied physicsmembrane sciencecondensed matterdomain formationphysical chemistrycritical size dependence