Faculty

Institution

Unit

Venue

Abigail Bigham

Associate Professor & Vice Chair for Undergraduate Studies

University of California, Los Angeles

Affiliations

the College

Anthropology

Institute for Quantitative and Computational Biosciences (qc Bio)

Abigail Bigham is currently serving as an Anthropology Associate Professor & Vice Chair for Undergraduate Studies at University of California, Los Angeles.

Honors

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Experiences

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Education

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Abigail Bigham

University of California, Los Angeles

Associate Professor & Vice Chair for Undergraduate Studies

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genetics human genetics evolutionary biology genomics population genetics adaptation physiology genome biology molecular biology human biology avian biology high altitude physical anthropology virology mammalian biology human physiology molecular genetics obstetrics and gynaecology evolutionary genetics genotype-phenotype association hiv applied physiology liver physiology avian medicine physiological research natural selection high-altitude adaptation bioinformatics vascular biology circulatory physiology respiratory medicine medical genetics host genetics comparative physiology mammalian physiology hypoxia (medicine) fetal growth peruvian quechua molecular physiology animal science reproductive biology reproductive science mutagenesis genetic admixture angiogenesis haplotype determination viral genetics short-term variability obstetrics fetal medicine high elevation animal genetics experimental biology biological evolution human exomes kabuki syndrome andean populations birth weight dna sequencing next-generation sequencing genome sequencing omics technologies mendelian disorder cancer genetics cancer genomics genome analysis sequence analysis population genomics parallel sequencing exome sequencing deep sequencing functional impact human high-altitude adaptation forward genetics hif pathway altitude-associated reductions

Notable Scholarly Works

Notable Federal Grants

Collaborators

Advances in Understanding Adaptive Hemoglobin Concentration at High Altitude. American Journal of Human Biology (2025)

health sciencesheme homeostasislaboratory medicinehuman biologymetabolismphysiology

Reply to Kleinsasser and Burtscher: Superimposed Acclimatization and Adaptation to Low and High Altitudes in Highlanders Compared to Lowlanders. Proceedings of the National Academy of Sciences (2025)

evolutionary ecologyecologyhigh elevationextreme environmentsadaptationevolutionary biology

Comparing Integrative Ventilatory and Renal Acid–Base Acclimatization in Lowlanders and Tibetan Highlanders During Ascent to 4,300 M. Proceedings of the National Academy of Sciences (2024)

Nicole A. JohnsonJessica A. DickensonBenjamin W.L. MacKenzieRodion IsakovichAnne KalkerJanne BoutenNicholas D.J. StrzalkowskiTaylor S. HarmanPontus HolmströmAjaya J. KunwarNilam ThakurSunil DhungelNima SherpaAbigail W. BighamTom D. BrutsaertTrevor A. Day

integrative ventilatoryrenal acid-base acclimatizationphysiology

Differential Splenic Responses to Hyperoxic Breathing at High Altitude in Sherpa and Lowlanders. Experimental Physiology (2024)

Pontus K. HolmströmTaylor S. HarmanAnne KalkerBethany SteinerElla HawkinsKelsey C. JorgensenKimberly T. ZhuAjaya J. KunwarNilam ThakurSunil DhungelNima SherpaTrevor A. DayErika K. SchagatayAbigail W. BighamTom D. Brutsaert

geneticsavian biologyrespiratory medicinedifferential splenic responseshigh altitudemolecular physiologyhuman biologyexperimental medicinehuman physiologyimmunologyexperimental biologyneurophysiologymammalian biologymammalian physiologyphysiology

Larger Spleens and Greater Splenic Contraction During Exercise May Be an Adaptive Characteristic of Nepali Sherpa at High‐Altitude. American Journal of Human Biology (2024)

Tom D. BrutsaertTaylor Shay HarmanAbigail W. BighamAnne KalkerKelsey C. JorgensenKimberly T. ZhuBethany C. SteinerElla HawkinsTrevor A. DayAjaya J. KunwarNilam ThakurSunil DhungelNima SherpaPontus K. Holmström

liver physiologyneurophysiologyexercise sciencegeneticsavian biologyapplied physiologylarger spleensgene expressionadaptive characteristicsport physiologyevolutionary biologymammalian biologyshort-term variabilityanimal physiologyexercise physiologynepali sherpahuman biologyhuman movementhuman physiologymammalian physiologyphysiology

De Novo Genome Assembly of Four Andean Potato Weevil Species ( Premnotrypes, Rhigopsidius ), the Primary Agricultural Pest of the Potato in South America. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Kelsey C. JorgensenObed A. GarciaJesús AlcázarKimberly K.O. WaldenAbigail W. BighamNorma Mujica MorónClorinda Vergara CobiánJulie J. LesnikChuanzhu Fan

geneticsplant genomicsplant sciencegenomicscrop scienceagricultural economicsmolecular biologyhorticulture researchgenome biologypest sciencesouth americagenome assemblybotanyprimary agricultural pestentomologysustainable agricultureagricultural biotechnologycropping systems

High-Altitude Andean H194R Hif2A Allele is a Hypomorphic Allele. Molecular Biology and Evolution (2023)

Kelsey JorgensenDaisheng SongJulien WeinsteinObed A GarciaLaurel N PearsonMaría InclánMaria Rivera-ChiraFabiola León-VelardeMelisa KiyamuTom D BrutsaertAbigail W BighamFrank S Lee

geneticspopulation geneticshuman geneticsevolutionary geneticshaplotype determinationmolecular geneticsmolecular biologygene evolutionhypomorphic allelebiological evolutionevolutionary biologymolecular evolutionallelic variant

The Legacy of Infectious Disease Exposure on the Genomic Diversity of Indigenous Southern Mexicans. Genome Biology and Evolution (2023)

Obed A GarciaKendall ArslanianDaniel WhorfSerena ThariathMark ShriverJun Z LiAbigail W Bigham

anthropologyinfectious disease exposuregenomicsinfectious diseasesindigenous peoplesindigenous southern mexicansgenomic diversitygenome biologyevolutionary biology

Genetic Adaptations to Potato Starch Digestion in the Peruvian Andes. American Journal of Physical Anthropology (2022)

Kelsey JorgensenObed A. GarciaMelisa KiyamuTom D. BrutsaertAbigail W. Bigham

geneticshuman geneticsanthropologyhuman evolutioncultural anthropologyphysical anthropologyenvironmental anthropologygenetic adaptationsbiological anthropologyevolutionary anthropologyadaptationevolutionary biology

Blood Lead Levels in Peruvian Adults Are Associated With Proximity to Mining and Dna Methylation. Environment International (2021)

Ainash ChildebayevaJaclyn M. GoodrichNathan ChestermanFabiola Leon-VelardeMaria Rivera-ChMelisa KiyamuTom D. BrutsaertAbigail W. BighamDana C. Dolinoy

peruvian adultsblood lead levelsenvironmental researchenvironmental sciencehuman-environment interactionspublic healthdna methylationepidemiology

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Abigail Bigham

Associate Professor & Vice Chair for Undergraduate Studies

University of California, Los Angeles

Affiliations

the College

Anthropology

Institute for Quantitative and Computational Biosciences (qc Bio)

Abigail Bigham is currently serving as an Anthropology Associate Professor & Vice Chair for Undergraduate Studies at University of California, Los Angeles.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Abigail Bigham

University of California, Los Angeles

Associate Professor & Vice Chair for Undergraduate Studies

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Advances in Understanding Adaptive Hemoglobin Concentration at High Altitude. American Journal of Human Biology (2025)

health sciencesheme homeostasislaboratory medicinehuman biologymetabolismphysiology

evolutionary ecologyecologyhigh elevationextreme environmentsadaptationevolutionary biology

Comparing Integrative Ventilatory and Renal Acid–Base Acclimatization in Lowlanders and Tibetan Highlanders During Ascent to 4,300 M. Proceedings of the National Academy of Sciences (2024)

integrative ventilatoryrenal acid-base acclimatizationphysiology

Differential Splenic Responses to Hyperoxic Breathing at High Altitude in Sherpa and Lowlanders. Experimental Physiology (2024)

Larger Spleens and Greater Splenic Contraction During Exercise May Be an Adaptive Characteristic of Nepali Sherpa at High‐Altitude. American Journal of Human Biology (2024)

Kelsey C. JorgensenObed A. GarciaJesús AlcázarKimberly K.O. WaldenAbigail W. BighamNorma Mujica MorónClorinda Vergara CobiánJulie J. LesnikChuanzhu Fan

High-Altitude Andean H194R Hif2A Allele is a Hypomorphic Allele. Molecular Biology and Evolution (2023)

Kelsey JorgensenDaisheng SongJulien WeinsteinObed A GarciaLaurel N PearsonMaría InclánMaria Rivera-ChiraFabiola León-VelardeMelisa KiyamuTom D BrutsaertAbigail W BighamFrank S Lee

The Legacy of Infectious Disease Exposure on the Genomic Diversity of Indigenous Southern Mexicans. Genome Biology and Evolution (2023)

Obed A GarciaKendall ArslanianDaniel WhorfSerena ThariathMark ShriverJun Z LiAbigail W Bigham

anthropologyinfectious disease exposuregenomicsinfectious diseasesindigenous peoplesindigenous southern mexicansgenomic diversitygenome biologyevolutionary biology

Genetic Adaptations to Potato Starch Digestion in the Peruvian Andes. American Journal of Physical Anthropology (2022)

Kelsey JorgensenObed A. GarciaMelisa KiyamuTom D. BrutsaertAbigail W. Bigham

Blood Lead Levels in Peruvian Adults Are Associated With Proximity to Mining and Dna Methylation. Environment International (2021)

Ainash ChildebayevaJaclyn M. GoodrichNathan ChestermanFabiola Leon-VelardeMaria Rivera-ChMelisa KiyamuTom D. BrutsaertAbigail W. BighamDana C. Dolinoy

peruvian adultsblood lead levelsenvironmental researchenvironmental sciencehuman-environment interactionspublic healthdna methylationepidemiology

1
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7
10 / page

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human adaptability

health science

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Northwestern University

public health

developmental biology

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Syracuse University

environmental research

health science

Mark Shriver

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James Reecy

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gene discovery

molecular metabolism

Scott Williams

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human genetics

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epigenetics

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genetic variation