Faculty

Institution

Unit

Venue

Alfred Ayala

Professor of Surgery Research Professor of Pathology and Laboratory Medicine

Brown University

Affiliations

Division of Biology and Medicine

Surgery

Warren Alpert Medical School

Molecular Biology, Cell Biology, & Biochemistry

Alfred Ayala is currently serving as a Division Of Biology And Medicine Professor of Surgery Research Professor of Pathology and Laboratory Medicine at Brown University.

Honors

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Experiences

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Education

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Alfred Ayala

Brown University

Professor of Surgery Research Professor of Pathology and Laboratory Medicine

You can click a keyword to filter the displayed items

immunology sepsis emergency medicine hematology inflammation critical care respiratory medicine immune responses medicine cell death trauma hemostasis apoptosis medicinal research innate immune system cytokines intensive care traumatology surgical care adaptive immune system resuscitation vascular biology cell signaling liver physiology clinical microbiology mammalian biology polymicrobial sepsis cellular physiology disaster medicine regenerative medicine endocrinology clinical immunology cellular immune responses hemorrhagic shock immunosuppression chronic inflammation thrombosis surgical oncology disease physiology circulatory physiology host response cell physiology general surgery applied physiology mammalian physiology acute lung injury renal function t-regulatory cell anti-inflammatory molecular physiology tissue physiology clinical surgery comparative physiology immunopathology human physiology host factors kupffer cells in vivo systems treatment effects critical system respiration (physiology) clinical medicine thanatology immune dysfunction fas ligand physiological research differential effects tumor necrosis factor hemorrhage-induced priming murine polymicrobial sepsis severe sepsis cytokine gene expression septic shock patients increased mortality haemorrhagic shock macrophage function infectious diseases immune cell function experimental medicine programmed cell death

Notable Scholarly Works

Notable Federal Grants

Collaborators

Herpes Virus Entry Mediator Signaling Blockade Produces Mortality in Neonatal Sepsis Through Induced Cardiac Dysfunction. Frontiers in Immunology (2024)

Michelle E. WakeleyNaomi-Liza DenningJihong JiangMonique E. De PaepeChun-Shiang ChungPing WangAlfred Ayala

public healthinflammationneonatologynephrologyvirologyinduced cardiac dysfunctionimmunologyneonatal sepsisemergency medicine

Invariant Natural Killer T Cells Modulate the Peritoneal Macrophage Response to Polymicrobial Sepsis. Journal of Surgical Research (2024)

Daithi S HeffernanTristen T ChunSean F MonaghanChun-Shiang ChungAlfred Ayala

clinical microbiologyperitoneal macrophage responsesurgical caresurgeryclinical immunologysepsisimmunologymedicinal researchsurgical pathologyimmune responsespolymicrobial sepsisadaptive immune systemcritical careinnate immune systemsurgical training

Rna Sequencing of Sepsis Patients Informs Tests to Quickly Diagnose Pathogens and Resistance. Research Square (Research Square) (2024)

Sean MonaghanJaewook ShinBrandon ArmsteadAlfred AyalaMaya CohenWilliam FairbrotherMitchell LevyKwesi LillardEmanuele RaggiGerard NauAlger Fredericks

pathogen detectionpublic healthclinical microbiologyinfectious diseasesnext-generation sequencingrna sequencingsepsisantimicrobial resistancemicrobiologydrug resistancepathogensmolecular diagnosticsdisease gene identificationdiagnostic microbiologyhigh throughput sequencinggene expressioninfection control

Application of Single Cell Multiomics Points to Changes in Chromatin Accessibility Near Calcitonin Receptor Like Receptor and a Possible Role for Adrenomedullin in the Post-Shock Lung. Frontiers in Medicine (2023)

Brandon E. ArmsteadChung Sunny LeeYaping ChenRunping ZhaoChun-Shiang ChungAlger M. FredericksSean F. MonaghanAlfred Ayala

proteomicscalcitonin receptorcell biologymedicinal researchsingle-cell analysischromosome biologyepigenomicspharmacologymedicinepost-shock lungreceptorschromatin accessibility

Lymphocyte Hvem/Btla Co-Expression After Critical Illness Demonstrates Severity Indiscriminate Upregulation, Impacting Critical Illness-Induced Immunosuppression. Frontiers in Medicine (2023)

Michelle E. WakeleyBrandon E. ArmsteadChyna C. GrayElizabeth W. TindalDaithi S. HeffernanChun-Shiang ChungAlfred Ayala

severity indiscriminate upregulationimmunosuppressioncritical illness-induced immunosuppressioncritical illnessimmunologyimmune responsesmedicine

Severity of Critical Illness Correlates With Cd3-Low Expression on Inkt-Cells Among Septic Surgical Patients. Inflammation Research (2023)

Daithi S. HeffernanChun-Shiang ChungAlfred Ayala

inflammationsepsisimmunologyrespiratory medicineseptic surgical patientsimmune responsesemergency medicinecritical care

Splenic Invariant Natural Killer T Cells Play a Significant Role in the Response to Polymicrobial Sepsis. Shock (2023)

Daithi S. HeffernanChun-Shiang ChungAlfred Ayala

infectious diseasesclinical immunologysepsisimmunologyimmune responsespolymicrobial sepsisadaptive immune systememergency medicineinnate immune system

Vista Nonredundantly Regulates Proliferation and Cd69Low γδ T Cell Accumulation in the Intestine in Murine Sepsis. Journal of Leukocyte Biology (2023)

Chyna C GrayBrandon E ArmsteadChun-Shiang ChungYaping ChenAlfred Ayala

vascular biologynephrologymurine sepsisimmunologycell biologyhematologyimmune responsescellular immune responsesemergency medicineinnate immune system

Contributors. Elsevier eBooks (2022)

Ron AltermanJeffrey E. ArleKerry BradleySergio CanaveroSteven M. FalowskiChad W. FarleyYakov GologorskyJianwen Wendy GuH. Louis JournéeJohn KastOlga KhazenJoachim K. KraussVignessh KumarMark LentRobert M. LevyAndres M. LozanoCharles MackelGeorge T. MandyburBryan L. McLaughlinDaniel R. MerrillAlon Y. MogilnerGabi MolnarGuillermo A. MonsalveRichard B. NorthYunseo Linda ParkJohn ParkerShrey PatelJulie G. PilitsisFrancisco A. PonceJason E. PopeAdolfo Ramirez-ZamoraLouis J. RasoJoshua M. RosenowJay L. ShilsPeter SingleKonstantin V. SlavinMichael D. StaudtMark M. SteckerHuy Q. Truong

Deep Rna Sequencing of Intensive Care Unit Patients With Covid-19. Scientific Reports (2022)

Alger M. FredericksMaximilian S. JentzschWilliam G. CioffiMaya CohenWilliam G. FairbrotherShivam J. GandhiElizabeth O. HarringtonGerard J. NauJonathan S. ReichnerCorey E. VentetuoloMitchell M. LevyAlfred AyalaSean F. Monaghan

public healthdeep rna sequencinggenome analysisvirologysequence analysisgenome sequencinggenomicsmolecular biologyintensive carescientific datacovid-19transcriptomics technologycomputational genomicscritical carebioinformaticsgenome biology

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Alfred Ayala

Professor of Surgery Research Professor of Pathology and Laboratory Medicine

Brown University

Affiliations

Division of Biology and Medicine

Surgery

Warren Alpert Medical School

Molecular Biology, Cell Biology, & Biochemistry

Alfred Ayala is currently serving as a Division Of Biology And Medicine Professor of Surgery Research Professor of Pathology and Laboratory Medicine at Brown University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Alfred Ayala

Brown University

Professor of Surgery Research Professor of Pathology and Laboratory Medicine

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Herpes Virus Entry Mediator Signaling Blockade Produces Mortality in Neonatal Sepsis Through Induced Cardiac Dysfunction. Frontiers in Immunology (2024)

Michelle E. WakeleyNaomi-Liza DenningJihong JiangMonique E. De PaepeChun-Shiang ChungPing WangAlfred Ayala

public healthinflammationneonatologynephrologyvirologyinduced cardiac dysfunctionimmunologyneonatal sepsisemergency medicine

Invariant Natural Killer T Cells Modulate the Peritoneal Macrophage Response to Polymicrobial Sepsis. Journal of Surgical Research (2024)

Daithi S HeffernanTristen T ChunSean F MonaghanChun-Shiang ChungAlfred Ayala

Rna Sequencing of Sepsis Patients Informs Tests to Quickly Diagnose Pathogens and Resistance. Research Square (Research Square) (2024)

Sean MonaghanJaewook ShinBrandon ArmsteadAlfred AyalaMaya CohenWilliam FairbrotherMitchell LevyKwesi LillardEmanuele RaggiGerard NauAlger Fredericks

Brandon E. ArmsteadChung Sunny LeeYaping ChenRunping ZhaoChun-Shiang ChungAlger M. FredericksSean F. MonaghanAlfred Ayala

proteomicscalcitonin receptorcell biologymedicinal researchsingle-cell analysischromosome biologyepigenomicspharmacologymedicinepost-shock lungreceptorschromatin accessibility

Lymphocyte Hvem/Btla Co-Expression After Critical Illness Demonstrates Severity Indiscriminate Upregulation, Impacting Critical Illness-Induced Immunosuppression. Frontiers in Medicine (2023)

Michelle E. WakeleyBrandon E. ArmsteadChyna C. GrayElizabeth W. TindalDaithi S. HeffernanChun-Shiang ChungAlfred Ayala

severity indiscriminate upregulationimmunosuppressioncritical illness-induced immunosuppressioncritical illnessimmunologyimmune responsesmedicine

Severity of Critical Illness Correlates With Cd3-Low Expression on Inkt-Cells Among Septic Surgical Patients. Inflammation Research (2023)

Daithi S. HeffernanChun-Shiang ChungAlfred Ayala

inflammationsepsisimmunologyrespiratory medicineseptic surgical patientsimmune responsesemergency medicinecritical care

Splenic Invariant Natural Killer T Cells Play a Significant Role in the Response to Polymicrobial Sepsis. Shock (2023)

Daithi S. HeffernanChun-Shiang ChungAlfred Ayala

infectious diseasesclinical immunologysepsisimmunologyimmune responsespolymicrobial sepsisadaptive immune systememergency medicineinnate immune system

Vista Nonredundantly Regulates Proliferation and Cd69Low γδ T Cell Accumulation in the Intestine in Murine Sepsis. Journal of Leukocyte Biology (2023)

Chyna C GrayBrandon E ArmsteadChun-Shiang ChungYaping ChenAlfred Ayala

vascular biologynephrologymurine sepsisimmunologycell biologyhematologyimmune responsescellular immune responsesemergency medicineinnate immune system

Contributors. Elsevier eBooks (2022)

Deep Rna Sequencing of Intensive Care Unit Patients With Covid-19. Scientific Reports (2022)

1
2
3
4
5
44
10 / page

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Johns Hopkins University

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